Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models.
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DOI: 10.1021/acs.analchem.9b04217
Abstract: Biochemical gradients across the intestinal epithelium play a major role in governing intestinal stem cell compartmentalization, differentiation dynamics, and organ-level self-renewal. However, scalable platforms that recapitulate the architecture and gradients present in vivo are absent.… read more here.
Keywords: phenotypic; photopatterned membranes; chemical gradients; membranes chemical ... See more keywords