[Membranous glomerulonephritis : An example of individualized medicine in nephrology].
Sign Up to like & getrecommendations! Published in 2019 at "Der Internist"
DOI: 10.1007/s00108-019-0573-z
Abstract: BACKGROUND Membranous glomerulonephritis (MGN) is the most frequent cause of a nephrotic syndrome in adults. It is an autoimmune disease caused by binding of autoantibodies to endogenous proteins expressed on glomerular podocytes. Antibody binding and activation… read more here.
Keywords: medicine; nephrology; medicine nephrology; membranous glomerulonephritis ... See more keywords
Validation of phospholipase A2 receptor direct immunofluorescence staining in the diagnosis of primary membranous glomerulonephritis.
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DOI: 10.1016/j.pathol.2020.04.003
Abstract: Distinguishing between primary and secondary subtypes of membranous glomerulonephritis (MGN) is critical for its clinical management. We prospectively compared direct immunofluorescence (DIF) staining for phospholipase A2 receptor (PLA2R) on frozen renal biopsy with the presence… read more here.
Keywords: diagnosis primary; direct immunofluorescence; dif; membranous glomerulonephritis ... See more keywords
Yi Shen An, a Chinese traditional prescription, ameliorates membranous glomerulonephritis induced by cationic bovine serum albumin in rats
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2021.2021947
Abstract: Abstract Context Yi Shen An (YSA) is an investigational composite of traditional Chinese medicine (Reference: 2010L000974) for the treatment of renal disease. Objective To investigate the protective effects of YSA against membranous glomerulonephritis (MGN). Materials… read more here.
Keywords: serum albumin; membranous glomerulonephritis; serum; bovine serum ... See more keywords
Concurrent mucous membrane pemphigoid and membranous glomerulonephritis in a patient with autoantibodies targeting the 1080 region of collagen XVII
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Dermatology"
DOI: 10.1111/bjd.17923
Abstract: There is a rare but documented association between the pemphigoid group of diseases and renal abnormalities, including membranous glomerulonephropathy, with an unknown immunopathogenic mechanism. Here, we report the case of a 68-year-old male patient presenting… read more here.
Keywords: targeting 1080; membrane pemphigoid; membranous glomerulonephritis; mucous membrane ... See more keywords
Membranous Glomerulonephritis as an Uncommon Presentation of Secondary Syphilis: A Reminder on Therapeutic Decision-Making in Clinical Practice
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DOI: 10.1177/2324709620967212
Abstract: Membranous glomerulonephritis is one of the common causes of nephrotic syndrome in the adult population. It is idiopathic in the majority of patients, but the secondary forms can be seen in the setting of autoimmune… read more here.
Keywords: clinical practice; membranous glomerulonephritis; syphilis; glomerulonephritis ... See more keywords
Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis.
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DOI: 10.1681/asn.2020121699
Abstract: BACKGROUND Autoantibodies binding to podocyte antigens cause idiopathic membranous glomerulonephritis (iMGN). However, it remains elusive how autoantibodies reach the subepithelial space because the glomerular filtration barrier (GFB) is size selective and almost impermeable for antibodies.… read more here.
Keywords: derived mir; glomerular endothelial; podocyte; membranous glomerulonephritis ... See more keywords
A Rare Adult Case with Diffuse Segmental Membranous Glomerulonephritis
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DOI: 10.2169/internalmedicine.56.8298
Abstract: A 71-year-old man with hypertension and diabetes mellitus presented with proteinuria. Laboratory data showed proteinuria of 3.1 g/g creatinine, serum albumin of 3.5 g/dL and serum creatinine of 1.03 mg/dL without autoantibodies. A renal biopsy… read more here.
Keywords: segmental membranous; membranous glomerulonephritis; adult case; diffuse segmental ... See more keywords
Case Report: Rapid renal response to venetoclax monotherapy in a CLL patient with secondary membranous glomerulonephritis
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DOI: 10.3389/fonc.2023.1108994
Abstract: Membranous glomerulonephritis (MGN) is a rare extra-hematological autoimmune complication of chronic lymphocytic leukemia (CLL), clinically characterized by nephrotic-range proteinuria and, less frequently, renal failure. Because of the rarity of this condition, there is no standardized… read more here.
Keywords: membranous glomerulonephritis; cll; venetoclax; renal response ... See more keywords
Primary Membranous Glomerulonephritis: The Role of Serum and Urine Biomarkers in Patient Management
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DOI: 10.3390/biomedicines7040086
Abstract: The detection of phospholipase A2 receptor (PLA2R) and thrombospondin domain containing 7A THSD7A among primary membranous glomerulonephritis (MGN) patients transformed the diagnosis, treatment monitoring, and prognosis. Anti-PLA2R can be detected in 70–90% of primary MGN… read more here.
Keywords: membranous glomerulonephritis; serum urine; pla2r; primary membranous ... See more keywords
Primary Membranous Glomerulonephritis-associated with Schistosomal Nephropathy
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DOI: 10.4103/ijn.ijn_7_18
Abstract: The association of bilharziasis with membranous nephropathy (MN) has long been debated. The relatively recent use of antibodies against the M-type phospholipase A2 receptor (PLA2R) has been proposed as a valuable tool to discriminate the… read more here.
Keywords: pla2r antibodies; glomerulonephritis associated; anti pla2r; membranous glomerulonephritis ... See more keywords