Memory CD4+ T cells enhance B‐cell responses to drifting influenza immunization
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Immunology"
DOI: 10.1002/eji.201847852
Abstract: Influenza A annually infects 5–10% of the world's human population resulting in one million deaths. Influenza causes annual epidemics and reinfects previously exposed individuals because of antigenic drift in the glycoprotein hemagglutinin. Due to antigenic… read more here.
Keywords: memory cd4; immunization; hab responses; drifting influenza ... See more keywords
The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis
Sign Up to like & getrecommendations! Published in 2021 at "Nature Immunology"
DOI: 10.1038/s41590-021-01090-1
Abstract: Antigen-specific memory CD4 + T cells can persist and confer rapid and efficient protection from microbial reinfection. However, the mechanisms underlying the long-term maintenance of the memory CD4 + T cell pool remain largely unknown.… read more here.
Keywords: cd4 cells; memory; virus; memory cd4 ... See more keywords
Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1715618115
Abstract: Significance The bone marrow (BM) harbors critical components of the adaptive immune system able to provide long-lasting protection against pathogens. Among those, CD4 memory T cells are potent helpers of immune reactions in secondary lymphoid… read more here.
Keywords: memory cd4; memory; bone marrow;
Transforming Growth Factor β Signaling Promotes HIV-1 Infection in Activated and Resting Memory CD4+ T Cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.00270-23
Abstract: Incomplete eradication of HIV-1 latency reservoirs remains the major hurdle in achieving a complete HIV/AIDS cure. Dissecting the facilitator of latency reservoir establishment may aid the discovery of druggable targets for HIV-1 cure. ABSTRACT Understanding… read more here.
Keywords: cd4 cells; infection; latency; memory ... See more keywords
The gC1qR Binding Site Mutant PCV2 Is a Potential Vaccine Strain That Does Not Impair Memory CD4+ T-Cell Generation by Vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00959-22
Abstract: PCV2 is one of the costliest pathogens in pigs worldwide. Usage of PCV2 vaccines can prevent the PCV2 infection-induced clinical syndromes but not the viral spread. ABSTRACT PCV2 has been reported to reduce the protective… read more here.
Keywords: memory cd4; infection; pcv2 infection; pcv2 ... See more keywords
Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Surgical Oncology"
DOI: 10.1186/s12957-021-02461-6
Abstract: Background Liver cancer is one of the most common malignant tumors in the world. T cell-mediated antitumor immune response is the basis of liver cancer immunotherapy. Objective To screen and analyze the RNAs associated with… read more here.
Keywords: cancer; activated memory; cell related; liver cancer ... See more keywords
Memory CD4 T cell-derived IL-2 synergizes with viral infection to exacerbate lung inflammation
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007989
Abstract: Defining the most penetrating correlates of protective memory T cells is key for designing improved vaccines and T cell therapies. Here, we evaluate how interleukin (IL-2) production by memory CD4 T cells, a widely held… read more here.
Keywords: memory cd4; infection; inflammation; cell ... See more keywords
Identification of FCER1G related to Activated Memory CD4+ T Cells Infiltration by Gene Co-expression Network and Construction of a Risk Prediction Module in Diffuse Large B-Cell Lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.849422
Abstract: Diffuse large B cell lymphoma (DLBCL) is a group of biologically heterogeneous tumors with different prognoses. The tumor microenvironment plays a vital role in the tumorigenesis and development of DLBCL, and activated memory CD4+ T… read more here.
Keywords: cd4 cells; memory cd4; gene; activated memory ... See more keywords
Atypical Human Effector/Memory CD4+ T Cells With a Naive-Like Phenotype
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02832
Abstract: The induction of adaptive immunological memory, mediated by T and B cells, plays an important role in protective immunity to pathogens induced by previous infections or vaccination. Naive CD4+ T cells that have been primed… read more here.
Keywords: memory cd4; cd4 cells; naive like; effector ... See more keywords
The extrinsic factors important to the homeostasis of allergen-specific memory CD4 T cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1080855
Abstract: Memory T cells, which are generated after the primary immune response to cognate antigens, possess unique features compared to naïve or effector T cells. These memory T cells are maintained for a long period of… read more here.
Keywords: allergen specific; cd4 cells; specific memory; memory ... See more keywords
Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.68388
Abstract: Antigen recognition through the T cell receptor (TCR) αβ heterodimer is one of the primary determinants of the adaptive immune response. Vaccines activate naïve T cells with high specificity to expand and differentiate into memory… read more here.
Keywords: cd4 cells; cd4; immunity; preexisting memory ... See more keywords