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   Articles with "memory deficits" as a keyword



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Memory deficits in Sprague Dawley rats with spontaneous ventriculomegaly

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recommendations! Published in 2020 at "Brain and Behavior"

DOI: 10.1002/brb3.1711

Abstract: Spontaneous ventriculomegaly has been observed in rats that were presumed normal. Because the external phenotype of these animals is unremarkable, they can be inadvertently included in behavioral experiments, despite the considerable enlargement of the ventricular… read more here.

Keywords: spontaneous ventriculomegaly; deficits sprague; memory deficits; rats spontaneous ... See more keywords

Acute depletion of complement C3 with cobra venom factor attenuates memory deficits induced by status epilepticus

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recommendations! Published in 2024 at "Epilepsia Open"

DOI: 10.1002/epi4.13030

Abstract: Status epilepticus (SE) significantly increases the risk for the development of unprovoked seizures, memory loss, and temporal lobe epilepsy. Our prior studies showed that SE increases complement C3 signaling in the hippocampus, which parallels memory… read more here.

Keywords: memory; venom factor; cobra venom; memory deficits ... See more keywords

Coumestrol pre‐treatment improves spatial learning and memory deficits following transient cerebral ischemia recruiting hippocampal GluR2 AMPA receptors

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recommendations! Published in 2022 at "Hippocampus"

DOI: 10.1002/hipo.23418

Abstract: Transient global ischemia is a leading cause of learning and memory dysfunction and induces a pattern of delayed neuronal death in the CA1 subfield of the hippocampus by down‐regulating GluR2 mRNA AMPA receptors in this… read more here.

Keywords: ischemia; ampa receptors; memory deficits; memory ... See more keywords
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Imperatorin ameliorates learning and memory deficits through BDNF/TrkB and ERK/CaMKIIα/CREB signaling in prenatally‐stressed female offspring

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recommendations! Published in 2020 at "Phytotherapy Research"

DOI: 10.1002/ptr.6692

Abstract: Prenatal stress (PS) can lead to impaired spatial learning and memory in offspring. Imperatorin (IMP) is a naturally occurring furanocoumarin with many pharmacological properties. However, the effects of IMP on cognitive impairment induced by PS… read more here.

Keywords: learning memory; camkii creb; bdnf trkb; memory deficits ... See more keywords
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Impaired intrinsic functional connectivity among medial temporal lobe and sub-regions related to memory deficits in intracranial dural arteriovenous fistula

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recommendations! Published in 2021 at "Neuroradiology"

DOI: 10.1007/s00234-021-02707-w

Abstract: The functional changes concerning memory deficits in dural arteriovenous fistula (dAVF) brain are inadequately understood. This study aimed to understand the functional connectivity alterations of brain regions widely affirmed for explicit and implicit memory functions… read more here.

Keywords: arteriovenous fistula; connectivity; memory deficits; dural arteriovenous ... See more keywords

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

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recommendations! Published in 2019 at "Acta Neuropathologica"

DOI: 10.1007/s00401-019-02017-9

Abstract: The bridging integrator 1 gene (BIN1) is a major genetic risk factor for Alzheimer’s disease (AD). In this report, we investigated how BIN1-dependent pathophysiological processes might be associated with Tau. We first generated a cohort… read more here.

Keywords: term; bin1; memory deficits; interaction ... See more keywords
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Reduction of advanced tau-mediated memory deficits by the MAP kinase p38γ

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recommendations! Published in 2020 at "Acta Neuropathologica"

DOI: 10.1007/s00401-020-02191-1

Abstract: Hyperphosphorylation of the neuronal tau protein contributes to Alzheimer’s disease (AD) by promoting tau pathology and neuronal and cognitive deficits. In contrast, we have previously shown that site-specific tau phosphorylation can inhibit toxic signals induced… read more here.

Keywords: kinase p38; tau; memory deficits; map kinase ... See more keywords

Puerarin and Amlodipine Improvement of d-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression

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recommendations! Published in 2017 at "Neurochemical Research"

DOI: 10.1007/s11064-017-2366-x

Abstract: Glucocorticoid receptors (GRs) exert actions on the hippocampus that are important for memory formation. There are correlations between vascular dysfunctions and GR-related gene expression. Both vascular dysfunction and GR gene expression decline occur during the… read more here.

Keywords: expression; expression decline; gene expression; memory deficits ... See more keywords

Melatonin Improves Memory Deficits in Rats with Cerebral Hypoperfusion, Possibly, Through Decreasing the Expression of Small-Conductance Ca2+-Activated K+ Channels

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recommendations! Published in 2019 at "Neurochemical Research"

DOI: 10.1007/s11064-019-02820-6

Abstract: This study investigated the expression pattern, regulation of expression, and the role of hippocampal small-conductance Ca2+-activated K+ (SK) channels in memory deficits after cerebral hypoperfusion (CHP) with or without melatonin treatment, in rats. Adults male… read more here.

Keywords: small conductance; expression; conductance ca2; memory deficits ... See more keywords

Necrostatin-1 Relieves Learning and Memory Deficits in a Zebrafish Model of Alzheimer's Disease Induced by Aluminum.

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recommendations! Published in 2022 at "Neurotoxicity research"

DOI: 10.1007/s12640-021-00463-6

Abstract: Aluminum (Al) is considered one of the environmental risk factors for Alzheimer's disease (AD). The present study aims to establish a zebrafish AD model induced by Al and explore if necrostation-1 (Nec-1), a specific inhibitor… read more here.

Keywords: zebrafish model; memory deficits; learning memory; memory ... See more keywords

Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation

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recommendations! Published in 2018 at "Brain, Behavior, and Immunity"

DOI: 10.1016/j.bbi.2018.06.004

Abstract: Maternal immune activation (MIA) is a common environmental insult on the developing brain and represents a risk factor for neurodevelopmental disorders. Animal models of in utero inflammation further revealed a causal link between maternal inflammatory… read more here.

Keywords: spatial memory; inflammation; brain; memory deficits ... See more keywords