Antibodies to Glutamate Facilitate Spatial Memory Formation in the Morris Water Maze in Aging C57BL/6 mice
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DOI: 10.1007/s10517-020-04812-x
Abstract: Intranasal administration of antibodies to glutamate in a dose of 250 μg/kg for two weeks facilitated spatial learning and memory formation in the Morris water maze in aging C57BL/6 mice. In animals treated with glutamate… read more here.
Keywords: memory formation; water maze; morris water; antibodies glutamate ... See more keywords
L1 retrotransposition alters the hippocampal genomic landscape enabling memory formation
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DOI: 10.1016/j.bbi.2016.12.018
Abstract: Somatic LINE-1 (L1) retrotransposition is a source of genomic mosaicism and potential phenotypic diversity among neurons during brain development. In the adult brain, L1 expression can be triggered by different environmental alterations, but its functional… read more here.
Keywords: memory formation; retrotransposition; alters hippocampal; retrotransposition alters ... See more keywords
The SETD6 Methyltransferase Plays an Essential Role in Hippocampus-Dependent Memory Formation
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DOI: 10.1016/j.biopsych.2019.05.022
Abstract: BACKGROUND Epigenetic mechanisms are critical for hippocampus-dependent memory formation. Building on previous studies that implicate the N-lysine methyltransferase SETD6 in the activation of nuclear factor-κB RELA (also known as transcription factor p65) as an epigenetic… read more here.
Keywords: memory formation; hippocampus dependent; memory; setd6 ... See more keywords
Ubiquitination of Histone H2B by Proteasome Subunit RPT6 Controls Histone Methylation Chromatin Dynamics During Memory Formation
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DOI: 10.1016/j.biopsych.2020.12.029
Abstract: BACKGROUND Posttranslational histone modifications play a critical role in the regulation of gene transcription underlying synaptic plasticity and memory formation. One such epigenetic change is histone ubiquitination, a process that is mediated by the ubiquitin-proteasome… read more here.
Keywords: memory formation; histone h2b; histone; memory ... See more keywords
Ventro-dorsal Hippocampal Pathway Gates Novelty-Induced Contextual Memory Formation
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DOI: 10.1016/j.cub.2020.09.074
Abstract: Summary Novelty facilitates memory formation and is detected by both the dorsal and ventral hippocampus. Although dentate granule cells (GCs) in the dorsal hippocampus are known to mediate the formation of novelty-induced contextual memories, the… read more here.
Keywords: memory formation; induced contextual; formation; contextual memory ... See more keywords
The effects of arousal and attention on emotional false memory formation
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DOI: 10.1016/j.jml.2019.03.010
Abstract: Previous research has shown that with reduced attention at encoding, false recognition of critical lures for negative arousing DRM lists were higher than positive arousing lists. The current study extends this research to examine the… read more here.
Keywords: false memory; attention; memory; memory formation ... See more keywords
Neurotransmission through dopamine D1 receptors is required for aversive memory formation and Arc activation in the cerebral cortex
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DOI: 10.1016/j.neures.2020.04.006
Abstract: Dopaminergic neurotransmission is considered to play an important role not only in reward-based learning, but also in aversive learning. Here, we investigated the role of dopaminergic neurotransmission via dopamine D1 receptors (D1Rs) in aversive memory… read more here.
Keywords: memory formation; cerebral cortex; aversive memory;
Riding the slow wave: Exploring the role of entrained low-frequency oscillations in memory formation
Sign Up to like & getrecommendations! Published in 2021 at "Neuropsychologia"
DOI: 10.1016/j.neuropsychologia.2021.107962
Abstract: Neural oscillations are proposed to support a variety of behaviors, including long-term memory, yet their functional significance remains an active area of research. Here, we explore a potential functional role of low-frequency cortical oscillations in… read more here.
Keywords: memory formation; frequency; low frequency; frequency oscillations ... See more keywords
Differential Effects of N-methyl-D-aspartate Receptors Activation in the Insular Cortex during Memory Formation and Updating of a Motivational Conflict Task
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DOI: 10.1016/j.neuroscience.2022.02.035
Abstract: Recognizing and weighing the value of stimuli is necessary for survival, as it allows living things to respond quickly and adequately to new experiences by comparing them with previous ones. Recent evidence shows that context… read more here.
Keywords: memory; task; motivational conflict; memory formation ... See more keywords
The Drosophila melanogaster tribbles pseudokinase is necessary for proper memory formation
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2017.06.006
Abstract: The tribbles (trbl) pseudokinases play important roles in signaling and physiology in multiple contexts, ranging from innate immunity to cancer, suggesting fundamental cellular functions for the trbls' gene products. Despite expression of the trbl pseudokinases… read more here.
Keywords: memory formation; drosophila melanogaster; trbl; proper memory ... See more keywords
Broad domains of histone 3 lysine 4 trimethylation are associated with transcriptional activation in CA1 neurons of the hippocampus during memory formation
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2019.04.009
Abstract: Transcriptional changes in the hippocampus are required for memory formation, and these changes are regulated by numerous post-translational modifications of chromatin-associated proteins. One of the epigenetic marks that has been implicated in memory formation is… read more here.
Keywords: memory formation; histone lysine; lysine trimethylation; h3k4me3 ... See more keywords