Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells
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DOI: 10.1126/sciadv.abl5621
Abstract: Chromosome instability is a critical event in cancer progression. Histone H3 variant CENP-A plays a fundamental role in defining centromere identity, structure, and function but is innately overexpressed in several types of solid cancers. In… read more here.
Keywords: epigenetic memory; oncogenic lncrnas; memory fragile; human cancer ... See more keywords