Evidence of memory generalization in contextual locomotor sensitization induced by amphetamine
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2016.10.018
Abstract: Graphical abstract Figure. No Caption available. HighlightsAfter 3 days of withdrawal, amphetamine sensitization is context‐dependent.After 28 days of withdrawal, animals expressed a generalized locomotor activity in novel context.Contextual generalization is prevented when sensitization was conducted… read more here.
Keywords: memory generalization; locomotor; locomotor sensitization; sensitization ... See more keywords
Endocannabinoids inhibit contextual fear memory generalization via hippocampal GABAergic synaptic transmission.
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2423974122
Abstract: Memory generalization allows an organism to adapt to new conditions, but overgeneralization of fear or traumatic experiences can be detrimental to survival and contributes to the development of various mental disorders. However, the cellular and… read more here.
Keywords: contextual fear; memory; fear memory; memory generalization ... See more keywords
Enhanced Medial Prefrontal Cortex and Hippocampal Activity Improves Memory Generalization in APP/PS1 Mice: A Multimodal Animal MRI Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.848967
Abstract: Memory generalization allows individuals to extend previously learned movement patterns to similar environments, contributing to cognitive flexibility. In Alzheimer’s disease (AD), the disturbance of generalization is responsible for the deficits of episodic memory, causing patients… read more here.
Keywords: memory generalization; activity; cognitive training; memory ... See more keywords