The guided fire from within: intratumoral administration of mRNA-based vaccines to mobilize memory immunity and direct immune responses against pathogen to target solid tumors
Sign Up to like & getrecommendations! Published in 2024 at "Cell Discovery"
DOI: 10.1038/s41421-024-00743-3
Abstract: We investigated a novel cancer immunotherapy strategy that effectively suppresses tumor growth in multiple solid tumor models and significantly extends the lifespan of tumor-bearing mice by introducing pathogen antigens into tumors via mRNA-lipid nanoparticles. The… read more here.
Keywords: mrna based; immune responses; immunity; memory immunity ... See more keywords