Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide
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DOI: 10.1158/1078-0432.ccr-20-3471
Abstract: Purpose: While the detection of AR-V7 in circulating tumor cells (CTC) is associated with resistance to abiraterone or enzalutamide in men with metastatic castration-resistant prostate cancer (mCRPC), it only accounts for a minority of this… read more here.
Keywords: abiraterone enzalutamide; cin; circulating tumor; treated abiraterone ... See more keywords
Expression of immune checkpoints on circulating tumor cells in men with metastatic prostate cancer
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DOI: 10.1186/s40364-021-00267-y
Abstract: Background A subset of men with metastatic prostate cancer (mPC) responds to immune checkpoint inhibitors, and there is an unmet need to predict those most likely to benefit. We characterized circulating tumor cells (CTCs) for… read more here.
Keywords: prostate cancer; immune checkpoints; expression; men mcrpc ... See more keywords