Production and application of menaquinone-7 (vitamin K2): a new perspective
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Microbiology and Biotechnology"
DOI: 10.1007/s11274-016-2169-2
Abstract: Menaquinone-7, a highly valuable member of the vitamin K series, has significant effects on preventing osteoporosis and cardiovascular disease besides its positive effects on blood coagulation. In this review, chemical and biological aspects of menaquinone-7… read more here.
Keywords: vitamin new; production; production application; menaquinone vitamin ... See more keywords
Bioconversion of farnesol and 1,4-dihydroxy-2-naphthoate to menaquinone by an immobilized whole-cell biocatalyst using engineered Elizabethkingia meningoseptica
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Microbiology and Biotechnology"
DOI: 10.1007/s11274-017-2382-7
Abstract: Menaquinone (MK) has important applications in the pharmaceutical and food industries. To increase the production rate (QP) of MK-4, we developed a straightforward biotransformation method for MK-4 synthesis directly from its precursors 1,4-dihydroxy-2-naphthoate (DHNA) and… read more here.
Keywords: farnesol; menaquinone; engineered elizabethkingia; elizabethkingia meningoseptica ... See more keywords
Highly Efficient Production of Menaquinone-7 from Glucose by Metabolically Engineered Escherichia coli.
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DOI: 10.1021/acssynbio.0c00568
Abstract: Menaquinone-7 (MK-7) possesses wide health and medical value, and the market demand for MK-7 has increased. Metabolic engineering for MK-7 production in Escherichia coli still remains challenging due to the characteristics of the competing quinone… read more here.
Keywords: production; escherichia coli; engineered coli; pathway ... See more keywords
Metabolic Engineering of the MEP Pathway in Bacillus subtilis for Increased Biosynthesis of Menaquinone-7.
Sign Up to like & getrecommendations! Published in 2019 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.9b00077
Abstract: Vitamin K is essential for blood coagulation and plays important roles in bone and cardiovascular health. Menaquinone-7 (MK-7) is one form of vitamin K that is especially useful due to its long half-life in the… read more here.
Keywords: mep pathway; metabolic engineering; engineering mep; menaquinone ... See more keywords
Evaluation of vitamin K (menaquinone-7) stability and secretion in glucose and glycerol-based media by Bacillus subtilis natto
Sign Up to like & getrecommendations! Published in 2019 at "Acta Alimentaria"
DOI: 10.1556/066.2019.48.4.1
Abstract: Menaquinone-7 (MK-7) is a type of vitamin K. MK-7 is produced via bacterial fermentation, and in order to reach the desired product purity, several downstream processing steps, including extraction, drying, ultrasonication, must be carried out.… read more here.
Keywords: secretion; evaluation vitamin; glycerol; vitamin ... See more keywords
Engineering Lactococcus lactis for Increased Vitamin K2 Production
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DOI: 10.3389/fbioe.2020.00191
Abstract: Cheese produced with Lactococcus lactis is the main source of vitamin K2 in the Western diet. Subclinical vitamin K2 deficiency is common, calling for foods with enhanced vitamin K2 content. In this study we describe… read more here.
Keywords: lactis; vitamin production; production; menaquinone ... See more keywords