MenB-FHbp Vaccine Protects Against Diverse Meningococcal Strains in Adolescents and Young Adults: Post Hoc Analysis of Two Phase 3 Studies
Sign Up to like & getrecommendations! Published in 2020 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-020-00319-0
Abstract: Two phase 3 studies in adolescents and young adults demonstrated that MenB-FHbp, a meningococcal serogroup B (MenB) vaccine, elicits protective immune responses after 2 or 3 doses based on serum bactericidal antibody assays using human… read more here.
Keywords: adolescents young; menb fhbp; post; vaccine ... See more keywords
Persistence of hSBA titers elicited by the meningococcal serogroup B vaccine menB-FHbp for up to 4 years after a 2- or 3-dose primary series and immunogenicity, safety, and tolerability of a booster dose through 26 months.
Sign Up to like & getrecommendations! Published in 2021 at "Vaccine"
DOI: 10.1016/j.vaccine.2021.06.005
Abstract: BACKGROUND To demonstrate extended protection against meningococcal serogroup B (MenB) disease after MenB-FHbp (bivalent rLP2086) vaccination, this study evaluated immunopersistence through 26 months following MenB-FHbp boosting after 2 or 3 primary doses in adolescents. STUDY DESIGN… read more here.
Keywords: menb; menb fhbp; persistence; booster ... See more keywords
Safety Surveillance of Bivalent Meningococcal Group B Vaccine, Vaccine Adverse Event Reporting System, 2014-2018.
Sign Up to like & getrecommendations! Published in 2020 at "Open forum infectious diseases"
DOI: 10.1093/ofid/ofaa516
Abstract: Background In October 2014, MenB-FHbp (Trumenba, Pfizer) became the first meningococcal group B vaccine licensed in the United States. It is approved for use in individuals aged 10-25 years. Our objective was to evaluate the… read more here.
Keywords: reporting; system; menb fhbp; safety ... See more keywords
Healthy Vaccinee Bias and MenB-FHbp Vaccine Effectiveness Against Gonorrhea
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DOI: 10.1097/olq.0000000000001793
Abstract: Healthy vaccinee bias likely did not confound earlier studies demonstrating the protective effect of outer-membrane vesicle serogroup B meningococcal vaccines against gonorrhea. Abstract Observational studies demonstrated 30% to 40% effectiveness of outer-membrane vesicle (OMV) meningococcal… read more here.
Keywords: healthy vaccinee; gonorrhea; menb fhbp; vaccinee bias ... See more keywords
Molecular characterization of invasive Neisseria meningitidis isolates collected in Lithuania (2009-2019) and estimation of serogroup B meningococcal vaccine 4CMenB and MenB-Fhbp coverage
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1136211
Abstract: Neisseria meningitidis causes invasive meningococcal disease (IMD), which is associated with significant mortality and long-term consequences, especially among young children. The incidence of IMD in Lithuania was among the highest in European Union/European Economic Area… read more here.
Keywords: lithuania; neisseria meningitidis; coverage; menb fhbp ... See more keywords