Meningeal inflammation and cerebral vasculitis during acute COVID-19 with spontaneous regression
Sign Up to like & getrecommendations! Published in 2021 at "Intensive Care Medicine"
DOI: 10.1007/s00134-021-06592-y
Abstract: A 46-year-old man with no significant past medical history was hospitalized in the intensive care unit (ICU) due to severe coronavirus disease 2019 (COVID-19) with acute respiratory distress syndrome. He was treated with corticosteroids, antibiotics,… read more here.
Keywords: meningeal inflammation; cerebral vasculitis; meningeal; inflammation cerebral ... See more keywords
Some observations over the article “Evaluation of the anastomoses between the ophthalmic artery and the middle meningeal artery by superselective angiography”
Sign Up to like & getrecommendations! Published in 2020 at "Surgical and Radiologic Anatomy"
DOI: 10.1007/s00276-020-02626-0
Abstract: We read with interest the article entitled “Evaluation of the anastomoses between the ophthalmic artery and the middle meningeal artery by superselective angiography” [1]. The article supplies some original insights on the anatomy of the… read more here.
Keywords: artery; article; ophthalmic artery; anatomy ... See more keywords
Neuroinflammation creates an immune regulatory niche at the meningeal lymphatic vasculature near the cribriform plate.
Sign Up to like & getrecommendations! Published in 2022 at "Nature immunology"
DOI: 10.1038/s41590-022-01158-6
Abstract: Meningeal lymphatics near the cribriform plate undergo lymphangiogenesis during neuroinflammation to drain excess fluid. Here, we hypothesized that lymphangiogenic vessels may acquire an altered phenotype to regulate immunity. Using single-cell RNA sequencing of meningeal lymphatics… read more here.
Keywords: near cribriform; cribriform plate; meningeal; neuroinflammation ... See more keywords
The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+ stimulation but not cortical spreading depression-induced afferent sensitization
Sign Up to like & getrecommendations! Published in 2018 at "Pain Reports"
DOI: 10.1097/pr9.0000000000000632
Abstract: Introduction: Cortical spreading depression (CSD) is believed to promote migraine headache by enhancing the activity and mechanosensitivity of trigeminal intracranial meningeal afferents. One putative mechanism underlying this afferent response involves an acute excitation of meningeal… read more here.
Keywords: spreading depression; cgrp; activation; meningeal ... See more keywords
Meningeal and vestibulocochlear nerve enhancement in neuromyelitis optica
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Neurology"
DOI: 10.1111/ene.13453
Abstract: Sir, The spectrum of neuromyelitis optica (NMO) broadly covers uncommon lesions located outside the core opticospinal lesions. Apart from the optic nerve, relapses involving the cranial nerves and cortical meningeal enhancement have rarely been described… read more here.
Keywords: hearing loss; neuromyelitis optica; enhancement; meningeal ... See more keywords
A mesothelium divides the subarachnoid space into functional compartments
Sign Up to like & getrecommendations! Published in 2023 at "Science"
DOI: 10.1126/science.adc8810
Abstract: The central nervous system is lined by meninges, classically known as dura, arachnoid, and pia mater. We show the existence of a fourth meningeal layer that compartmentalizes the subarachnoid space in the mouse and human… read more here.
Keywords: space; layer; brain; subarachnoid space ... See more keywords
Meningeal Mechanisms and the Migraine Connection.
Sign Up to like & getrecommendations! Published in 2023 at "Annual review of neuroscience"
DOI: 10.1146/annurev-neuro-080422-105509
Abstract: Migraine is a complex neurovascular pain disorder linked to the meninges, a border tissue innervated by neuropeptide-containing primary afferent fibers chiefly from the trigeminal nerve. Electrical or mechanical stimulation of this nerve surrounding large blood… read more here.
Keywords: migraine connection; meningeal mechanisms; meningeal; mechanisms migraine ... See more keywords
Functional Investigation of Meningeal Lymphatic System in Experimental Intracerebral Hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.121.037834
Abstract: Supplemental Digital Content is available in the text. Background: Promotion of hematoma resolution in a timely manner reduces intracerebral hemorrhage (ICH) brain injury induced by toxic blood components and subsequent neuroinflammation. The meningeal lymphatic system… read more here.
Keywords: function; meningeal lymphatic; lymphatic system; intracerebral hemorrhage ... See more keywords
Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.151683
Abstract: Subpial cortical demyelination is an important component of multiple sclerosis (MS) pathology contributing to disease progression, yet mechanism(s) underlying its development remain unclear. Compartmentalized inflammation involving the meninges may drive this type of injury. Given… read more here.
Keywords: white matter; lesion; activity; subpial cortical ... See more keywords
Current understanding of meningeal and cerebral vascular function underlying migraine headache
Sign Up to like & getrecommendations! Published in 2018 at "Cephalalgia"
DOI: 10.1177/0333102418771350
Abstract: Background The exact mechanisms underlying the onset of a migraine attack are not completely understood. It is, however, now well accepted that the onset of the excruciating throbbing headache of migraine is mediated by the… read more here.
Keywords: migraine; migraine headache; cranial meninges; meningeal ... See more keywords
Surgical management of sacral meningeal cysts by obstructing the communicating holes with muscle graft
Sign Up to like & getrecommendations! Published in 2019 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-019-2998-x
Abstract: BackgroundThe surgical indication and treatment of sacral meningeal cyst have not been well established and current methods are usually accompanied by complications and recurrence. The aim of this study is to discuss the treatment of… read more here.
Keywords: meningeal cysts; cyst; obstructing communicating; muscle graft ... See more keywords