Characterization of dural sinus-associated lymphatic vasculature in human Alzheimer’s dementia subjects
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.07.020
Abstract: Recent reports describing lymphatic vasculature in the meninges have challenged the traditional understanding of interstitial solute clearance from the central nervous system, although the significance of this finding in human neurological disease remains unclear. To… read more here.
Keywords: vasculature; alzheimer; lymphatic vasculature; vasculature human ... See more keywords
Improving the function of meningeal lymphatic vessels to promote brain edema absorption after TBI.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurotrauma"
DOI: 10.1089/neu.2022.0150
Abstract: Brain edema is the most common and fatal complication after traumatic brain injury. Meningeal lymphatic vessels (MLVs) are the conduits that transport cerebrospinal fluid (CSF) and macromolecules to deep extracranial cervical lymph nodes (dCLNs). After… read more here.
Keywords: function; meningeal lymphatic; brain; absorption ... See more keywords
Meningeal Lymphatic vasculature in health and disease
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000711
Abstract: Purpose of review The recent (re)discovery of the meningeal lymphatic has brought a new player in brain neurophysiology. This review highlights the state of the current research on the meningeal lymphatic vasculature, from its specific… read more here.
Keywords: vasculature health; lymphatic vasculature; health disease; meningeal lymphatic ... See more keywords
Meningeal lymphatic network: The middleman of neuroinflammation
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Neuroimmunology"
DOI: 10.1111/cen3.12563
Abstract: The central nervous system was long thought to be an immune‐privileged organ, notably because of its lack of conventional lymphatic drainage. Years of scientific observations and the recent (re)discovery of the meningeal lymphatic system has… read more here.
Keywords: network middleman; meningeal lymphatic; lymphatic network; middleman neuroinflammation ... See more keywords
Functional Investigation of Meningeal Lymphatic System in Experimental Intracerebral Hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.121.037834
Abstract: Supplemental Digital Content is available in the text. Background: Promotion of hematoma resolution in a timely manner reduces intracerebral hemorrhage (ICH) brain injury induced by toxic blood components and subsequent neuroinflammation. The meningeal lymphatic system… read more here.
Keywords: function; meningeal lymphatic; lymphatic system; intracerebral hemorrhage ... See more keywords
Cranial Bone Transport Promotes Angiogenesis, Neurogenesis, and Modulates Meningeal Lymphatic Function in Middle Cerebral Artery Occlusion Rats
Sign Up to like & getrecommendations! Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.121.037912
Abstract: Background: Ischemic stroke is a leading cause of death and disability worldwide. However, the time window for quickly dissolving clots and restoring cerebral blood flow, using tissue-type plasminogen activator treatment is rather limited, resulting in… read more here.
Keywords: function; bone; meningeal lymphatic; mcao rats ... See more keywords
Gene expression in meningeal lymphatic endothelial cells following traumatic brain injury in mice
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0273892
Abstract: Meningeal lymphatic vessels transport both the cerebrospinal fluid and interstitial fluid to the deep cervical lymph nodes. Traumatic brain injury (TBI) is accompanied by meningeal injury. We hypothesized that the TBI-induced meningeal injury would damage… read more here.
Keywords: meningeal lymphatic; brain; expression; group ... See more keywords
The Interplay between Meningeal Lymphatic Vessels and Neuroinflammation in Neurodegenerative Diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x21666221115150253
Abstract: Meningeal lymphatic vessels (MLVs) are essential for the drainage of cerebrospinal fluid, macromolecules, and immune cells in the central nervous system. They play critical roles in modulating neuroinflammation in neurodegenerative diseases. Dysfunctional MLVs have been… read more here.
Keywords: neuroinflammation; meningeal lymphatic; lymphatic vessels; mlvs ... See more keywords
Assessment of Meningeal Lymphatics in the Parasagittal Dural Space: A Prospective Feasibility Study Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Sign Up to like & getrecommendations! Published in 2023 at "Korean Journal of Radiology"
DOI: 10.3348/kjr.2022.0980
Abstract: Objective Meningeal lymphatic vessels are predominantly located in the parasagittal dural space (PSD); these vessels drain interstitial fluids out of the brain and contribute to the glymphatic system. We aimed to investigate the ability of… read more here.
Keywords: meningeal; contrast enhanced; dynamic contrast; meningeal lymphatic ... See more keywords
Effects of Sound Interventions on the Permeability of the Blood–Brain Barrier and Meningeal Lymphatic Clearance
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12060742
Abstract: The meningeal lymphatic, or glymphatic, system is receiving increasing attention from the scientific community. Recent work includes noninvasive techniques to demonstrate relationships between blood–brain barrier (BBB) activity and the glymphatic system in the human central… read more here.
Keywords: music; music sound; meningeal lymphatic; brain ... See more keywords
Borneol-driven meningeal lymphatic drainage clears amyloid-β peptide to attenuate Alzheimer-like phenotype in mice
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.76133
Abstract: Rationale: The accumulation and clearance of amyloid-β (Aβ) peptides play a crucial role in the pathogenesis of Alzheimer's disease (AD). The (re)discovery of meningeal lymphatic vessels in recent years has focused attention on the lymphatic… read more here.
Keywords: clearance; lymphatic drainage; lymphatic clearance; borneol ... See more keywords