Pericarditis due to Neisseria meningitidis serogroup W135
Sign Up to like & getrecommendations! Published in 2018 at "IDCases"
DOI: 10.1016/j.idcr.2018.02.009
Abstract: Neisseria meningitidis is a well-recognized cause of bacterial meningitis. Although less common, N. meningitidis can also involve extra-meningeal sites, including the pericardium. The frequency of such extra-meningeal clinical manifestations differs depending on N. meningitidis serogroup.… read more here.
Keywords: serogroup w135; pericarditis due; pericarditis; meningitidis serogroup ... See more keywords
Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready Neisseria meningitidis Serogroup X Vaccine Antigens.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical biology"
DOI: 10.1021/acschembio.7b01057
Abstract: Studies on the polymerization mode of Neisseria meningitidis serogroup X capsular polymerase CsxA recently identified a truncated construct that can be immobilized and used for length controlled on-column production of oligosaccharides. Here, we combined the… read more here.
Keywords: combined chemical; fully synthetic; elongation; meningitidis serogroup ... See more keywords
Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A
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DOI: 10.1038/s41467-020-18464-y
Abstract: O-Acetylation of the capsular polysaccharide (CPS) of Neisseria meningitidis serogroup A (NmA) is critical for the induction of functional immune responses, making this modification mandatory for CPS-based anti-NmA vaccines. Using comprehensive NMR studies, we demonstrate… read more here.
Keywords: acetylation; capsule; structural mechanistic; mechanistic basis ... See more keywords
Neisseria meningitidis Serogroup C Clonal Complex 10217 Outbreak in West Kpendjal Prefecture, Togo 2019
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01923-21
Abstract: The recent emergence of an invasive NmC strain in Togo is an example of the changing bacterial meningitis epidemiology in the meningitis belt post-MACV. The current epidemiology includes the regional circulation of various non-NmA serogroups,… read more here.
Keywords: neisseria meningitidis; meningitis; outbreak; meningitidis serogroup ... See more keywords
Genomic surveillance of Neisseria meningitidis serogroup B invasive strains: Diversity of vaccine antigen types, Brazil, 2016-2018
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DOI: 10.1371/journal.pone.0243375
Abstract: Background Neisseria meningitidis serogroup B remains a prominent cause of invasive meningococcal disease (IMD) in Brazil. Because two novel protein-based vaccines against serogroup B are available, the main purpose of this study was to provide… read more here.
Keywords: diversity; antigen types; vaccine antigen; meningitidis serogroup ... See more keywords
Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia
Sign Up to like & getrecommendations! Published in 2017 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2308.170259
Abstract: In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253… read more here.
Keywords: neisseria meningitidis; resistant clade; penicillin resistant; meningitidis serogroup ... See more keywords
Construction and protective immunogenicity of DNA vaccine pNMB0315 against Neisseria meningitidis serogroup B.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.8255
Abstract: Neisseria meningitidis (N. meningitidis) is a major cause of meningitis and sepsis. Capsular polysaccharide‑based vaccines against serogroups A, C, Y, and W135 are available; however, the development of a vaccine against N. meningitidis serogroup B (NMB) has been problematic. NMB0315 is… read more here.
Keywords: pnmb0315; meningitidis serogroup; neisseria meningitidis; vaccine ... See more keywords