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Published in 2020 at "Intensive Care Medicine"
DOI: 10.1007/s00134-019-05901-w
Abstract: Central nervous system (CNS) infections represent 2.9% of the infections encountered in the intensive care unit (ICU) [1]. Among them, infectious meningitis and encephalitis, regardless of their community or healthcare-associated origin, often have dramatic consequences,…
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Keywords:
meningitis encephalitis;
care;
management;
infectious meningitis ... See more keywords
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Published in 2017 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2016.09.022
Abstract: We compared an FDA cleared molecular meningitis/encephalitis panel to lab developed viral PCRs and bacterial culture. Of the 67 viral PCR or bacterial culture-positive samples, 92.5% were positive for the same target by the panel.…
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Keywords:
panel;
comparative evaluation;
evaluation filmarray;
meningitis encephalitis ... See more keywords
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Published in 2021 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2021.115394
Abstract: Ten controlled studies evaluated antimicrobial use following implementation of the FilmArray meningitis and encephalitis panel versus usual care. Only one-half of studies identified significant reductions in antibiotic duration, with 8/10 reporting modest reductions for acyclovir.…
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Keywords:
filmarray meningitis;
encephalitis panel;
meningitis encephalitis;
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Published in 2019 at "IDCases"
DOI: 10.1016/j.idcr.2019.e00516
Abstract: A BioFire FilmArray Meningitis/Encephalitis test was performed on a 7-month old child suspected for bacterial meningitis. Two pathogens were detected, Neisseria meningitidis and cytomegalovirus (CMV). We verified the filmarray meningitis/encephalitis test by pan-bacterial assay to…
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Keywords:
meningitis;
meningitis encephalitis;
filmarray meningitis;
test ... See more keywords
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Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.141
Abstract: The multiplex polymerase chain reaction (PCR) test for meningitis/encephalitis (ME) is an assay that is available to detect 14 organisms in 2 hours from the cerebral spinal fluid. The primary objective was to assess the…
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Keywords:
pcr;
antimicrobial stewardship;
meningitis encephalitis;
test ... See more keywords
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Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.1835
Abstract: Abstract Background Large epidemiological studies evaluating the etiologies, management decisions and outcomes of infants and children with meningitis and encephalitis in the United States (US) are lacking. Methods Infants (
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Keywords:
speaker;
epidemiology;
infants children;
meningitis encephalitis ... See more keywords
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Published in 2020 at "Pediatric Emergency Care"
DOI: 10.1097/pec.0000000000002180
Abstract: Meningitis and encephalitis (ME) are important causes of morbidity and mortality worldwide. Patients suspected of having ME are often hospitalized and started on empiric antimicrobial treatment, because of the potential adverse consequences of delaying the…
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Keywords:
rapid diagnostic;
encephalitis biofire;
diagnostic tests;
meningitis encephalitis ... See more keywords
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Published in 2020 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00311-20
Abstract: The impact of diagnostic stewardship and testing algorithms on the utilization and performance of the FilmArray meningitis/encephalitis (ME) panel has received limited investigation. We performed a retrospective single-center cohort study assessing all individuals with suspected…
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Keywords:
filmarray meningitis;
panel;
yield;
stewardship testing ... See more keywords
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Published in 2019 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01592-19
Abstract: Molecular testing of cerebrospinal fluid (CSF) using the BioFire FilmArray meningitis/encephalitis (FA-M/E) panel permits rapid, simultaneous pathogen detection. Due to the broad spectrum of targeted organisms, FA-M/E testing may be restricted to patients with abnormal…
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Keywords:
filmarray meningitis;
encephalitis panel;
cerebrospinal fluid;
pleocytosis ... See more keywords
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Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02774-21
Abstract: Based on our comparative analysis of performances of the diagnostic assays, we propose an algorithm for the use of both syndromic and specific assays, for an optimal care of the meningitis/encephalitis threat in adult and…
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Keywords:
adult pediatric;
meningitis encephalitis;
adult;
performance ... See more keywords
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Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.05144-22
Abstract: The diagnosis of infectious meningitis and encephalitis relies mostly on specific PCR and culturing methods, but commercial syndromic panel assays are bringing a change in diagnostics. With multiplexed analysis, the identification of the pathogen is…
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Keywords:
meningitis;
meningitis encephalitis;
encephalitis panel;
qiastat meningitis ... See more keywords