Neutrophil Extracellular Traps in Children With Meningococcal Sepsis
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Critical Care Medicine"
DOI: 10.1097/pcc.0000000000001496
Abstract: Objectives: Children with meningococcal sepsis are highly at risk for fulminant disease, multiple organ failure, and death. Recently, neutrophil extracellular traps levels have been indicated as a marker for severity in different kinds of sepsis.… read more here.
Keywords: sepsis; neutrophil extracellular; dna; children meningococcal ... See more keywords
Rare case of meningococcal sepsis-induced testicular failure, primary hypothyroidism and hypoadrenalism: Is there a link?
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Case Reports"
DOI: 10.1136/bcr-2018-224437
Abstract: Severe illness can lead to multiple transient endocrinopathies. In adult patients, neuroendocrine alterations include sick euthyroid syndrome, an increase in corticosteroid levels, increase in prolactin levels, decreased insulin growth factor 1 levels and hypogonadism. We… read more here.
Keywords: meningococcal sepsis; severe illness; primary hypothyroidism; case ... See more keywords
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis
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DOI: 10.1186/s40560-017-0217-0
Abstract: BackgroundFulminant meningococcal sepsis, characterized by overwhelming innate immune activation, mostly affects young people and causes high mortality. This study aimed to investigate the effect of targeting two key molecules of innate immunity, complement component C5,… read more here.
Keywords: sepsis; group; inflammatory response; cd14 ... See more keywords
Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model
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DOI: 10.1371/journal.ppat.1009299
Abstract: Neisseria meningitidis (the meningococcus) remains a major cause of bacterial meningitis and fatal sepsis. This commensal bacterium of the human nasopharynx can cause invasive diseases when it leaves its niche and reaches the bloodstream. Blood-borne… read more here.
Keywords: sepsis; sustained bacteremia; pilus retraction; outcome meningococcal ... See more keywords