Clustered intergenic region sequences as predictors of factor H Binding Protein expression patterns and for assessing Neisseria meningitidis strain coverage by meningococcal vaccines
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DOI: 10.1371/journal.pone.0197186
Abstract: Factor H binding protein (fHbp) is a major protective antigen in 4C-MenB (Bexsero®) and Trumenba®, two serogroup B meningococcal vaccines, wherein expression level is a determinant of protection. Examination of promoter-containing intergenic region (IGR) sequences… read more here.
Keywords: protein; meningococcal vaccines; coverage; expression ... See more keywords
Meningococcal Disease in Pediatric Age: A Focus on Epidemiology and Prevention
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DOI: 10.3390/ijerph19074035
Abstract: Meningococcal disease is caused by Neisseria meningitidis; 13 serogroups have been identified and differentiated from each other through their capsular polysaccharide. Serotypes A, B, C, W, X, and Y are responsible for nearly all infections… read more here.
Keywords: disease; age; meningococcal vaccines; meningococcal disease ... See more keywords
Meningococcal Vaccines: Challenges and Prospects
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DOI: 10.3390/vaccines8040738
Abstract: Neisseria meningitidis is a gram-negative bacterium that causes a severe acute infection, called the meningococcal disease [...]. read more here.
Keywords: challenges prospects; vaccines challenges; meningococcal vaccines;