Pharmacokinetics of a cytosine arabinoside subcutaneous protocol in dogs with meningoencephalomyelitis of unknown aetiology.
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DOI: 10.1111/jvp.12980
Abstract: Cytosine arabinoside (CA) is a commonly used treatment for dogs with meningoencephalomyelitis of unknown aetiology (MUE) with various proposed protocols, many requiring 24 hours (h) of hospitalization or two visits within 24 h. This is a unidirectional… read more here.
Keywords: meningoencephalomyelitis unknown; unknown aetiology; range; subcutaneous protocol ... See more keywords
Cytosine arabinoside constant rate infusion without subsequent subcutaneous injections for the treatment of dogs with meningoencephalomyelitis of unknown origin
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DOI: 10.1136/vr.106019
Abstract: Background The administration of cytosine arabinoside (CA) by continuous rate infusion (CRI) at the time of diagnosis has been shown to improve the 3-month survival of dogs diagnosed with meningoencephalomyelitis of unknown origin (MUO), compared… read more here.
Keywords: meningoencephalomyelitis unknown; subcutaneous injections; unknown origin; rate infusion ... See more keywords
Evaluation of treatment with a combination of mycophenolate mofetil and prednisolone in dogs with meningoencephalomyelitis of unknown etiology: a retrospective study of 86 cases (2009–2017)
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DOI: 10.1186/s12917-020-02414-3
Abstract: Background Combination therapy with glucocorticoids and adjunctive immunomodulating drugs has been generally accepted as a standard treatment regimen for meningoencephalomyelitis of unknown etiology (MUE). We hypothesized that treatment with MMF as an adjunctive agent along… read more here.
Keywords: meningoencephalomyelitis unknown; combination; unknown etiology; etiology ... See more keywords
Differential T-cell responses in dogs with meningoencephalomyelitis of unknown origin compared to healthy controls
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DOI: 10.3389/fvets.2022.925770
Abstract: Meningoencephalomyelitis of unknown origin (MUO) is a common disorder in dogs that results in mononuclear inflammation in the brain and/or spinal cord. MUO is presumed to be autoimmune but specific immunological aberrations have not been… read more here.
Keywords: cell; unknown origin; meningoencephalomyelitis unknown; healthy controls ... See more keywords
Treatment With Cytarabine at Initiation of Therapy With Cyclosporine and Glucocorticoids for Dogs With Meningoencephalomyelitis of Unknown Origin Is Not Associated With Improved Outcomes
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DOI: 10.3389/fvets.2022.925774
Abstract: Meningoencephalomyelitis of unknown origin (MUO) is a common disorder of dogs that results in significant morbidity and mortality. The ideal treatment regimen is not known but a second immunosuppressive agent is often utilized in combination… read more here.
Keywords: time; unknown origin; meningoencephalomyelitis unknown; cyclosporine ... See more keywords
New insights into the treatment of meningoencephalomyelitis of unknown origin since 2009: A review of 671 cases
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DOI: 10.3389/fvets.2023.1114798
Abstract: “Meningoencephalomyelitis of unknown origin” (MUO)—a collective term for a group of clinically-indistinguishable (but pathologically distinct) autoimmune diseases of the CNS—has become increasingly commonly recognized throughout the world. In the 1960s−1980s the focus was primarily on… read more here.
Keywords: treatment; unknown origin; since 2009; meningoencephalomyelitis unknown ... See more keywords