Atypical Michaelis-Menten kinetics in cytochrome P450 enzymes: A focus on substrate inhibition.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2019.08.017
Abstract: Abstract The widespread applications of the century-old Michaelis-Menten kinetics in the characterization of drug-metabolizing cytochrome P450 enzymes have persisted since their discovery in the 1950s. This is a concern given preceding reports of atypical Michaelis-Menten… read more here.
Keywords: michaelis menten; menten kinetics; cytochrome p450; p450 enzymes ... See more keywords
An alternative approach to Michaelis-Menten kinetics that is based on the renormalization group.
Sign Up to like & getrecommendations! Published in 2018 at "Mathematical biosciences"
DOI: 10.1016/j.mbs.2017.11.012
Abstract: We apply to Michaelis-Menten kinetics an alternative approach to the study of Singularly Perturbed Differential Equations, that is based on the Renormalization Group (SPDERG). To this aim, we first rebuild the perturbation expansion for Michaelis-Menten… read more here.
Keywords: renormalization group; michaelis menten; alternative approach; menten kinetics ... See more keywords
How Michaelis–Menten kinetics can represent ecosystem-scale respiration: scale and applicability
Sign Up to like & getrecommendations! Published in 2025 at "Environmental Research Letters"
DOI: 10.1088/1748-9326/adc31a
Abstract: Terrestrial ecosystem respiration (Re) is a crucial component of the carbon cycle and is expected to increase with anthropogenic warming. The temperature response of Re is typically parameterized using temperature sensitivity Q10, which describes the… read more here.
Keywords: temperature; michaelis menten; respiration; ecosystem ... See more keywords
Beyond conventional models: integer and fractional order analysis of nonlinear Michaelis-Menten kinetics in immobilised enzyme reactors
Sign Up to like & getrecommendations! Published in 2024 at "Engineering Computations"
DOI: 10.1108/ec-03-2024-0238
Abstract: PurposeThis study explores the immobilisation of enzymes within porous catalysts of various geometries, including spheres, cylinders and flat pellets. The objective is to understand the irreversible Michaelis-Menten kinetic process within immobilised enzymes through advanced mathematical… read more here.
Keywords: michaelis menten; method; analysis; research ... See more keywords