Menthol-induced activation of TRPM8 receptors increases cutaneous blood flow across the dermatome.
Sign Up to like & getrecommendations! Published in 2021 at "Microvascular research"
DOI: 10.1016/j.mvr.2021.104271
Abstract: Topical menthol-based analgesics increase skin blood flow (SkBF) through transient receptor potential melastatin 8 (TRPM8) receptor-dependent activation of sensory nerves and endothelium-derived hyperpolarization factors. It is unclear if menthol-induced TRPM8 activation mediates a reflex change… read more here.
Keywords: across dermatome; menthol induced; blood; activation ... See more keywords
UCP1 and TRPM8 Expression in the Brown Fat Did Not Affect the Restriction of Menthol-Induced Hyperthermia by Estradiol in Ovariectomized Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.67.130
Abstract: Estradiol (E2) modulates the central and peripheral thermoregulatory responses to cold. Menthol is an agonist of transient receptor potential melastatin type 8 (TRPM8), which is a peripheral cold receptor. E2 suppresses menthol-induced elevation of body… read more here.
Keywords: ovariectomized rats; estradiol; ucp1 trpm8; menthol induced ... See more keywords