7-Methoxyderivative of tacrine is a ‘foot-in-the-door’ open-channel blocker of GluN1/GluN2 and GluN1/GluN3 NMDA receptors with neuroprotective activity in vivo
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DOI: 10.1016/j.neuropharm.2018.08.010
Abstract: Abstract N‐methyl‐d‐aspartate receptors (NMDARs) are ionotropic glutamate receptors that mediate excitatory neurotransmission in the mammalian central nervous system (CNS), and their dysregulation results in the aetiology of many CNS syndromes. Several NMDAR modulators have been… read more here.
Keywords: door open; open channel; glun1; meota ... See more keywords