Posterodorsal Medial Amygdala Urocortin-3, GABA, and Glutamate Mediate Suppression of LH Pulsatility in Female Mice
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DOI: 10.1101/2022.07.07.499104
Abstract: The posterodorsal subnucleus of the medial amygdala (MePD) is an upstream modulator of the hypothalamic-pituitary-gonadal (HPG) and hypothalamic-pituitary-adrenal (HPA) axes. Inhibition of MePD urocortin-3 (Ucn3) neurons prevents psychological stress-induced suppression of LH pulsatility while blocking… read more here.
Keywords: ucn3 neurons; mepd; mepd ucn3; medial amygdala ... See more keywords
GABA Signaling in the Posterodorsal Medial Amygdala Mediates Stress-induced Suppression of LH Pulsatility in Female Mice
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DOI: 10.1210/endocr/bqac197
Abstract: Abstract Psychological stress is linked to infertility by suppressing the hypothalamic GnRH pulse generator. The posterodorsal subnucleus of the medial amygdala (MePD) is an upstream regulator of GnRH pulse generator activity and displays increased neuronal… read more here.
Keywords: mepd; gaba; induced suppression; stress induced ... See more keywords
Role of Posterodorsal Medial Amygdala Urocortin-3 in Pubertal Timing in Female Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.893029
Abstract: Post-traumatic stress disorder impedes pubertal development and disrupts pulsatile LH secretion in humans and rodents. The posterodorsal sub-nucleus of the medial amygdala (MePD) is an upstream modulator of the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator,… read more here.
Keywords: stress; female mice; pubertal timing; mepd ... See more keywords