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Published in 2020 at "Lung"
DOI: 10.1007/s00408-020-00379-6
Abstract: Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL‐5 receptor and IL‐5, respectively, suppressing the corresponding pathways. No specific biomarkers have been proposed to evaluate…
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Keywords:
eosinophilic asthma;
mepolizumab benralizumab;
severe eosinophilic;
proteomic study ... See more keywords
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Published in 2020 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000508936
Abstract: Background: New anti-IL-5 antibodies, mepolizumab and benralizumab, have recently been approved for severe asthma, sharing the same inclusion criteria. Objective: To contribute on biomarkers research leading to the personalized choice, we investigated L-selectin, Krebs von…
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Keywords:
mepolizumab benralizumab;
severe eosinophilic;
personalized approach;
patients treated ... See more keywords
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Published in 2022 at "Internal Medicine"
DOI: 10.2169/internalmedicine.8180-21
Abstract: Objective Switching from mepolizumab to benralizumab has been reported to significantly improve both asthma control and the lung function. However, the data on its efficacy in elderly patients with severe eosinophilic asthma are limited. This…
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Keywords:
eosinophilic asthma;
elderly patients;
asthma;
severe eosinophilic ... See more keywords