Mepolizumab for the treatment of chronic rhinosinusitis with nasal polyps in adults
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2023.2181794
Abstract: ABSTRACT Introduction The treatment paradigm for chronic rhinosinusitis with nasal polyps (CRSwNP) is complex, consisting of a combination of conservative, medical and surgical management. High rates of recurrence despite current standard of care has led… read more here.
Keywords: nasal polyps; mepolizumab treatment; chronic rhinosinusitis; rhinosinusitis nasal ... See more keywords
S81 Does adherence to inhaled therapy change following initiation of mepolizumab in the treatment of severe asthma?
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.87
Abstract: Introduction and objectives Anti IL-5 agents are used in addition to routine therapies: inhaled corticosteroids (ICS), long acting beta2-agonists (LABA), long acting muscarinic antagonists (LAMA), Leukotriene Receptor Antagonists (LRTA), and short acting beta2-agonists (SABA), in… read more here.
Keywords: initiation mepolizumab; ocs; initiation; mepolizumab treatment ... See more keywords
Potential impact of mepolizumab in stepping down anti-osteporotic treatment in corticosteroid-dependent asthma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1183156
Abstract: Oral corticosteroids (OCS) are commonly used for the acute management of severe asthma exacerbations or as maintenance therapy; however, chronic use is associated with significant toxicities, e.g., osteoporosis. In the REal worlD Effectiveness and Safety… read more here.
Keywords: potential impact; mepolizumab; dependent asthma; mepolizumab treatment ... See more keywords
Efficacy of mepolizumab treatment in oral corticosteroid-dependent severe eosinophilic asthma patients with chronic rhinosinusitis with nasal polyps: single center, real life study
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DOI: 10.3906/sag-1912-62
Abstract: Background/aim Oral corticosteroid (OCS)-dependent severe eosinophilic asthma with chronic rhinosinusitis with nasal polyps (SEA-CRSwNP) would be a suitable phenotype for mepolizumab treatment. This study evaluated the short-term efficacy of mepolizumab treatment in OCS-dependent SEA-CRSwNP. Materials… read more here.
Keywords: efficacy mepolizumab; week; treatment; study ... See more keywords
A Single Center Experience of Super-Responders Among Severe Asthma Patients Receiving Treatment with Mepolizumab
Sign Up to like & getrecommendations! Published in 2022 at "Turkish Thoracic Journal"
DOI: 10.5152/turkthoracj.2022.22023
Abstract: OBJECTIVE: Anecdotal reports among clinicians treating severe asthma patients with novel add-on treatments such as mepolizumab suggest that a fraction of these patients may experience a much more dramatic benefit from these agents than reported… read more here.
Keywords: treatment; severe asthma; mepolizumab treatment; super responders ... See more keywords