Preparation of Carbon-14 Labeled 2-(2-mercaptoacetamido)-3-phenylpropanoic Acid as Metallo-beta-lactamases Inhibitor (MBLI), for Coadministration with Beta-lactam Antibiotics.
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DOI: 10.2174/1570179416666190423114704
Abstract: AIM AND OBJECTIVE Bacteria could become resistant to β-lactam antibiotics through production of β- lactamase enzymes like metallo-β-lactamase. 2-(2-mercaptoacetamido)-3-phenylpropanoic acid was reported as a model inhibitor for this enzyme. In order to elucidate the mechanism… read more here.
Keywords: mercaptoacetamido phenylpropanoic; carbon labeled; beta; phenylpropanoic acid ... See more keywords