Articles with "mercaptopurine cytotoxicity" as a keyword



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PACSIN2 as a modulator of autophagy and mercaptopurine cytotoxicity: mechanisms in lymphoid and intestinal cells

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Published in 2023 at "Life Science Alliance"

DOI: 10.26508/lsa.202201610

Abstract: This study evaluates the role of PACSIN2 in autophagy modulation and its impact on mercaptopurine cytotoxicity in lymphoid and intestinal models. PACSIN2 variants are associated with gastrointestinal effects of thiopurines and thiopurine methyltransferase activity through… read more here.

Keywords: mercaptopurine cytotoxicity; cytotoxicity; intestinal cells; pacsin2 ... See more keywords