Elucidating the binding mechanism of thione‐containing mercaptopurine and thioguanine drugs to small gold clusters
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DOI: 10.1002/jcc.26216
Abstract: Density functional theory methods were employed to clarify the adsorption/desorption behaviors of the thione‐containing mercaptopurine and thioguanine drugs on the gold surface using both small Au6 and Au8 clusters as model reactants. Structural features, thermodynamic… read more here.
Keywords: containing mercaptopurine; gold clusters; gold; mercaptopurine thioguanine ... See more keywords
VALIDATION OF 6-MERCAPTOPURINE AND 6-THIOGUANINE IN DRIED BLOOD SPOT BY ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY
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DOI: 10.22159/ijap.2018.v10s1.91
Abstract: Objective: This study aimed to obtain an optimal and validated method of analyzing 6-mercaptopurine (6-MP) and 6-thioguanine (6-TG) simultaneouslyin dried blood spot samples using ultra high-performance liquid chromatography-tandem mass spectrometry.Method: Separation was performed with a… read more here.
Keywords: chromatography tandem; blood spot; dried blood; liquid chromatography ... See more keywords