166. A Phase 2b/3 Study to Evaluate the Efficacy and Safety of an Investigational Respiratory Syncytial Virus (RSV) Antibody, Clesrovimab, in Healthy Preterm and Full-Term Infants
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DOI: 10.1093/ofid/ofae631.003
Abstract: Abstract Background Clesrovimab is an investigational, long-acting monoclonal antibody (mAb) targeting site IV of the fusion protein for the prevention of RSV lower respiratory tract infection in infants. Methods This phase 2b/3 double-blind, randomized, placebo-controlled… read more here.
Keywords: rahway usa; merck; merck inc; merck sharp ... See more keywords
P-1196. Drug-Drug Interactions (DDIs) With Letermovir (LET) for Cytomegalovirus (CMV) Prophylaxis in Pediatric (Birth to < 18 years of age) Hematopoietic Cell Transplant (HCT) Recipients
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DOI: 10.1093/ofid/ofae631.1380
Abstract: Abstract Background HCT recipients receive multiple medications post-transplant, increasing the potential for DDIs. LET, a CMV terminase complex inhibitor approved for CMV prophylaxis in adult CMV-seropositive allogeneic HCT recipients, has the potential for DDIs with… read more here.
Keywords: merck; hct; research; let ... See more keywords
1097-P: Glycemic Control and Safety Profile of Insulin Glargine 300 U/mL in Older Adults—REALI Pooled Data Analysis
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DOI: 10.2337/db19-1097-p
Abstract: Despite an increasing number of patients with type 2 diabetes (T2D) in the older population, clinical evidence for different therapeutic strategies in the elderly is poor. Therefore, we used the REALI pooled database, which includes… read more here.
Keywords: merck sharp; dohme corp; sanofi; sharp dohme ... See more keywords