Differences in Merkel Cell Carcinoma Presentation and Outcomes Among Racial and Ethnic Groups.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2023.0061
Abstract: Importance Racial and ethnic differences in skin cancer outcomes are understudied. Delineating these differences in Merkel cell carcinoma (MCC) is needed to better understand this rare disease. Objective To determine how MCC presentation and outcomes… read more here.
Keywords: differences merkel; black patients; merkel cell; racial ethnic ... See more keywords
Adjuvant Radiotherapy for Surgically Resected Stage III Merkel Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA surgery"
DOI: 10.1001/jamasurg.2023.7016
Abstract: This case-control study evaluates whether adjuvant radiotherapy is associated with overall survival among patients with surgically resected stage III Merkel cell carcinoma. read more here.
Keywords: stage iii; adjuvant radiotherapy; surgically resected; merkel cell ... See more keywords
Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular oncology"
DOI: 10.1002/1878-0261.70107
Abstract: Merkel cell carcinoma (MCC) is a highly aggressive disease with the poorest prognosis among skin cancers, originally posited to be derived from Merkel cells. Emerging evidence, however, suggests other potential origins for MCC, including hematological… read more here.
Keywords: novel molecular; molecular targets; cell; merkel cell ... See more keywords
Lymph node ratio predicts efficacy of postoperative radiation therapy in nonmetastatic Merkel cell carcinoma: A population‐based analysis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4773
Abstract: After radical resection of a nonmetastatic Merkel cell carcinoma (M0 MCC), postoperative radiation therapy (RT) is recommended as it improves survival. However, the role of RT in specific subgroups of M0 MCC is unclear. We… read more here.
Keywords: cell carcinoma; merkel cell; postoperative radiation; radiation therapy ... See more keywords
Avelumab for the treatment of locally advanced or metastatic Merkel cell carcinoma-A multicenter real-world experience in Israel.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5890
Abstract: BACKGROUND Merkel cell carcinoma (MCC) is a rare and aggressive malignancy of the skin, affecting predominantly the fair-skinned older population exposed to high levels of ultraviolet light. Immune suppression is considered a significant risk factor.… read more here.
Keywords: cell carcinoma; merkel cell; avelumab; treatment ... See more keywords
Changes in Merkel cell oncoprotein antibodies after radiation therapy in curatively treated Merkel cell carcinoma and association with recurrence
Sign Up to like & getrecommendations! Published in 2024 at "Cancer"
DOI: 10.1002/cncr.35507
Abstract: Serum antibodies to the Merkel oncoprotein (AMERK) are detectable in approximately 50% of patients with Merkel cell carcinoma (MCC) and can be used to monitor for recurrence. The objective of this study was to characterize… read more here.
Keywords: cell; radiation therapy; merkel cell; cell carcinoma ... See more keywords
Diagnostic clues for differentiating Merkel cell carcinoma from lymphoma in fine-needle aspiration cytology.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic cytopathology"
DOI: 10.1002/dc.24872
Abstract: Nodal fine needle aspiration (FNA) is usually the first procedure in the work-up of malignancy of unknown primary. Merkel cell carcinoma (MCC) is an aggressive cutaneous cancer more common in Caucasians but rare among Asians.… read more here.
Keywords: carcinoma; needle aspiration; fine needle; merkel cell ... See more keywords
Merkel cell carcinoma presenting as a malignant pleural effusion post-COVID-19 hospitalization: A case report and literature review.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic cytopathology"
DOI: 10.1002/dc.24882
Abstract: Merkel cell carcinoma (MCC) is a rare, highly aggressive neuroendocrine carcinoma of the skin, associated with immunosuppression, UV light exposure, and the Merkel cell polyomavirus (MCPyV). Cases of metastatic MCC diagnosed in body fluid cytology… read more here.
Keywords: carcinoma; case; merkel cell; cell ... See more keywords
Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes
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DOI: 10.1002/ijc.32503
Abstract: Viruses can inhibit host autophagy through multiple mechanisms, and evasion of autophagy plays an important role in immune suppression and viral oncogenesis. Merkel cell polyomavirus (MCPyV) T‐antigens are expressed and involved in the pathogenesis of… read more here.
Keywords: cell polyomavirus; autophagy; merkel cell; mcpyv ... See more keywords
Transcriptomic analyses reveal three distinct molecular subgroups of Merkel cell carcinoma with differing prognoses
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34425
Abstract: Merkel cell carcinoma (MCC) is a cutaneous neuroendocrine malignancy with a poor prognosis and an unknown cell of origin. Proffered cells of origin include epithelial stem cells of the hair follicle or interfollicular epidermis, dermal… read more here.
Keywords: cell; cell carcinoma; merkel cell; three distinct ... See more keywords
Droplet‐digital PCR assay to detect Merkel cell polyomavirus sequences in chorionic villi from spontaneous abortion affected females
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29213
Abstract: Droplet‐digital polymerase chain reaction (ddPCR) technique was set up to detect/quantify Merkel cell polyomavirus (MCPyV) DNA in clinical specimens, including chorionic villi and peripheral blood mononuclear cells (PBMCs) from spontaneous abortion (SA)‐affected females. This ddPCR… read more here.
Keywords: chorionic villi; droplet digital; dna; merkel cell ... See more keywords