Differences in Merkel Cell Carcinoma Presentation and Outcomes Among Racial and Ethnic Groups.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2023.0061
Abstract: Importance Racial and ethnic differences in skin cancer outcomes are understudied. Delineating these differences in Merkel cell carcinoma (MCC) is needed to better understand this rare disease. Objective To determine how MCC presentation and outcomes… read more here.
Keywords: differences merkel; black patients; merkel cell; racial ethnic ... See more keywords
Lymph node ratio predicts efficacy of postoperative radiation therapy in nonmetastatic Merkel cell carcinoma: A population‐based analysis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4773
Abstract: After radical resection of a nonmetastatic Merkel cell carcinoma (M0 MCC), postoperative radiation therapy (RT) is recommended as it improves survival. However, the role of RT in specific subgroups of M0 MCC is unclear. We… read more here.
Keywords: cell carcinoma; merkel cell; postoperative radiation; radiation therapy ... See more keywords
Avelumab for the treatment of locally advanced or metastatic Merkel cell carcinoma-A multicenter real-world experience in Israel.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5890
Abstract: BACKGROUND Merkel cell carcinoma (MCC) is a rare and aggressive malignancy of the skin, affecting predominantly the fair-skinned older population exposed to high levels of ultraviolet light. Immune suppression is considered a significant risk factor.… read more here.
Keywords: cell carcinoma; merkel cell; avelumab; treatment ... See more keywords
Diagnostic clues for differentiating Merkel cell carcinoma from lymphoma in fine-needle aspiration cytology.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic cytopathology"
DOI: 10.1002/dc.24872
Abstract: Nodal fine needle aspiration (FNA) is usually the first procedure in the work-up of malignancy of unknown primary. Merkel cell carcinoma (MCC) is an aggressive cutaneous cancer more common in Caucasians but rare among Asians.… read more here.
Keywords: carcinoma; needle aspiration; fine needle; merkel cell ... See more keywords
Merkel cell carcinoma presenting as a malignant pleural effusion post-COVID-19 hospitalization: A case report and literature review.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic cytopathology"
DOI: 10.1002/dc.24882
Abstract: Merkel cell carcinoma (MCC) is a rare, highly aggressive neuroendocrine carcinoma of the skin, associated with immunosuppression, UV light exposure, and the Merkel cell polyomavirus (MCPyV). Cases of metastatic MCC diagnosed in body fluid cytology… read more here.
Keywords: carcinoma; case; merkel cell; cell ... See more keywords
Merkel cell polyomavirus oncoproteins induce microRNAs that suppress multiple autophagy genes
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32503
Abstract: Viruses can inhibit host autophagy through multiple mechanisms, and evasion of autophagy plays an important role in immune suppression and viral oncogenesis. Merkel cell polyomavirus (MCPyV) T‐antigens are expressed and involved in the pathogenesis of… read more here.
Keywords: cell polyomavirus; autophagy; merkel cell; mcpyv ... See more keywords
Transcriptomic analyses reveal three distinct molecular subgroups of Merkel cell carcinoma with differing prognoses
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34425
Abstract: Merkel cell carcinoma (MCC) is a cutaneous neuroendocrine malignancy with a poor prognosis and an unknown cell of origin. Proffered cells of origin include epithelial stem cells of the hair follicle or interfollicular epidermis, dermal… read more here.
Keywords: cell; cell carcinoma; merkel cell; three distinct ... See more keywords
Droplet‐digital PCR assay to detect Merkel cell polyomavirus sequences in chorionic villi from spontaneous abortion affected females
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29213
Abstract: Droplet‐digital polymerase chain reaction (ddPCR) technique was set up to detect/quantify Merkel cell polyomavirus (MCPyV) DNA in clinical specimens, including chorionic villi and peripheral blood mononuclear cells (PBMCs) from spontaneous abortion (SA)‐affected females. This ddPCR… read more here.
Keywords: chorionic villi; droplet digital; dna; merkel cell ... See more keywords
Baseline ultrasound and FDG‐PET/CT imaging in Merkel cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.27193
Abstract: Merkel cell carcinoma (MCC) is a cutaneous tumor with a high tendency to metastasize, and a significant proportion of patients have metastases at first presentation. This study aims to determine the value of baseline ultrasound… read more here.
Keywords: cell carcinoma; baseline ultrasound; pet imaging; merkel cell ... See more keywords
Best practices in surgical and nonsurgical management of head and neck Merkel cell carcinoma: An update
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23483
Abstract: Merkel cell carcinoma (MCC) is a rare, highly aggressive cutaneous neuroendocrine carcinoma. Controversy exists regarding optimal management of MCC as high‐quality randomized studies and clinical trials are limited, and physicians are bound to interpret highly… read more here.
Keywords: cell carcinoma; merkel cell; best practices; mcc ... See more keywords
Merkel cell carcinoma: Epidemiology, pathogenesis, diagnosis and therapy
Sign Up to like & getrecommendations! Published in 2017 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-017-9433-0
Abstract: Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with a neuroendocrine phenotype. Incidence varies according to the geographic regions but is overall increasing. Different risk factors have been identified namely advanced age,… read more here.
Keywords: therapy; merkel cell; cell carcinoma; epidemiology ... See more keywords