Chemometrically assisted development and validation of LC–MS/MS method for the analysis of potential genotoxic impurities in meropenem active pharmaceutical ingredient
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DOI: 10.1016/j.jpba.2017.06.061
Abstract: Graphical abstract Figure. No Caption available. HighlightsNovel LC–MS/MS method for simultaneous determination of 3 PGIs in meropenem API.A Box‐Behnken design was utilized for method development.Grid point search methodology was implemented aiming to obtain the optimal… read more here.
Keywords: methodology; potential genotoxic; analysis; method ... See more keywords