Vancomycin Analogue Restores Meropenem Activity against NDM-1 Gram-Negative Pathogens.
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DOI: 10.1021/acsinfecdis.8b00011
Abstract: New Delhi metallo-β-lactamase-1 (NDM-1) is the major contributor to the emergence of carbapenem resistance in Gram-negative pathogens (GNPs) and has caused many clinically available β-lactam antibiotics to become obsolete. A clinically approved inhibitor of metallo-β-lactamase… read more here.
Keywords: inhibitor; gram negative; meropenem activity; negative pathogens ... See more keywords