Simultaneous quantification of cefepime, meropenem, ciprofloxacin, moxifloxacin, linezolid and piperacillin in human serum using an isotope‐dilution HPLC–MS/MS method
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DOI: 10.1016/j.jpba.2018.01.031
Abstract: &NA; The aim of the current study was to develop and validate a robust multi‐analyte high performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS) method for simultaneous quantification of cefepime, meropenem, ciprofloxacin, moxifloxacin, linezolid and piperacillin,… read more here.
Keywords: quantification; cefepime; moxifloxacin; meropenem ciprofloxacin ... See more keywords
Use of the Hollow-Fiber Infection Model to Measure the Effect of Combination Therapy of Septic Shock Exposures of Meropenem and Ciprofloxacin against Intermediate and Resistant Pseudomonas aeruginosa Clinical Isolates
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DOI: 10.1128/aac.02140-21
Abstract: Meropenem-ciprofloxacin combination therapy was compared to the respective monotherapy in a Hollow-Fiber Infection Model against two Pseudomonas aeruginosa isolates. Following initial kill of ∼ 5-logs by each monotherapy, rapid regrowth occurred within 24 h, reaching… read more here.
Keywords: fiber infection; combination therapy; combination; hollow fiber ... See more keywords