Does nephrotoxicity develop less frequently when vancomycin is combined with imipenem-cilastatin than with meropenem? A comparative study
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DOI: 10.1080/23744235.2019.1619934
Abstract: Abstract Introduction: Nephrotoxicity is a frequent complication of vancomycin therapy. Experimental studies in different animal species have demonstrated the attenuation of vancomycin-associated nephrotoxicity with cilastatin administration. This study aimed to evaluate if imipenem-cilastatin attenuates vancomycin-associated… read more here.
Keywords: vancomycin; meropenem vancomycin; cilastatin vancomycin; imipenem cilastatin ... See more keywords
Concentrations of Co-Administered Meropenem and Vancomycin in Spinal Tissues Relevant for the Treatment of Pyogenic Spondylodiscitis—An Experimental Microdialysis Study
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12050907
Abstract: Co-administration of meropenem and vancomycin has been suggested as a systemic empirical antibiotic treatment of pyogenic spondylodiscitis. The aim of this study was, in an experimental porcine model, to evaluate the percentage of an 8-h… read more here.
Keywords: pyogenic spondylodiscitis; vancomycin; meropenem vancomycin; treatment pyogenic ... See more keywords