Factors influencing the induction of high affinity antibodies to Plasmodium falciparum merozoite antigens and how affinity changes over time
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DOI: 10.1038/s41598-018-27361-w
Abstract: Understanding the functional characteristics of naturally acquired antibodies against P. falciparum merozoite antigens is crucial for determining the protective functions of antibodies. Affinity (measured as kd) of naturally acquired antibodies against two key targets of… read more here.
Keywords: affinity; merozoite antigens; antibody; time ... See more keywords
Measuring antibody avidity to Plasmodium falciparum merozoite antigens using a multiplex immunoassay approach
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DOI: 10.1186/s12936-020-03243-3
Abstract: Antibodies (Ab) play a significant role in immunity to Plasmodium falciparum malaria. Usually, following repeated exposure to pathogens, affinity maturation and clonal selection take place, resulting in increased antibody avidity. However, some studies suggest affinity… read more here.
Keywords: merozoite antigens; plasmodium falciparum; antibody avidity; avidity ... See more keywords