Antibodies against a short region of PfRipr inhibit Plasmodium falciparum merozoite invasion and PfRipr interaction with Rh5 and SEMA7A
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DOI: 10.1038/s41598-020-63611-6
Abstract: Plasmodium falciparum merozoite invasion into erythrocytes is an essential step of the blood-stage cycle, survival of parasites, and malaria pathogenesis. P. falciparum merozoite Rh5 interacting protein (PfRipr) forms a complex with Rh5 and CyRPA in… read more here.
Keywords: merozoite invasion; rh5; invasion; pfripr ... See more keywords
The Plasmodium falciparum Nuclear Protein Phosphatase NIF4 Is Required for Efficient Merozoite Invasion and Regulates Artemisinin Sensitivity
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DOI: 10.1128/mbio.01897-22
Abstract: Protein phosphorylation regulates a multitude of cellular processes. The eukaryotic FCP1 phosphatase acts as a CTD-phosphatase to critically balance the phosphorylation status of the CTD of the RNAPII, controlling the accurate execution of the transcription… read more here.
Keywords: phosphatase; falciparum; pfnif4; merozoite invasion ... See more keywords
Plasmodium falciparum GAP40 Plays an Essential Role in Merozoite Invasion and Gametocytogenesis
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DOI: 10.1128/spectrum.01434-23
Abstract: Red blood cell invasion is central to the pathogenesis of the malaria parasite, and the parasite proteins involved in this process are potential therapeutic targets. Gliding motility powers merozoite invasion and is driven by a… read more here.
Keywords: pfgap40; plasmodium; invasion; membrane ... See more keywords