Xylan microparticles for controlled release of mesalamine: Production and physicochemical characterization.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.116929
Abstract: Xylan extracted from corn cobs was used to produce mesalamine-loaded xylan microparticles (XMP5-ASA) by cross-linking polymerization using a non-hazardous cross-linking agent. The microparticles were characterized by thermal analysis (DSC/TG), X-ray diffraction (XRD), Infrared spectroscopy (FTIR-ATR)… read more here.
Keywords: mesalamine; asa; drug; xylan microparticles ... See more keywords
Shenling Baizhu San ameliorates ulcerative colitis by regulating the gut microbiota and its tryptophan metabolites: A complementary medicine to mesalamine.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115145
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Shenling Baizhu San (SBS) is commonly employed to improve gastrointestinal dysfunction in patients with ulcerative colitis (UC) in China. SBS combined with mesalamine has been demonstrated to result in improve its curative effects… read more here.
Keywords: shenling baizhu; tryptophan metabolites; mesalamine; medicine ... See more keywords
Design and Preparation of Copper(II)–Mesalamine Complex Functionalized on Silica-Coated Magnetite Nanoparticles and Study of Its Catalytic Properties for Green and Multicomponent Synthesis of Highly Substituted 4H-Chromenes and Pyridines
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c00731
Abstract: In the present study, a green and ecofriendly nanocatalyst was synthesized through functionalization of 2,4,6-trichloro-1,3,5-triazine (TCT) and mesalamine on silica-coated magnetic nanoparticles (MNPs), then coordination with Cu2+ without agglomeration, consecutively. The silica-coated MNPs functionalized with… read more here.
Keywords: mesalamine; mesalamine complex; synthesis; tct mesalamine ... See more keywords
Comparative assessment of budesonide-MMX and mesalamine in active, mild-to-moderate ulcerative colitis: a systematic review and network meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.14051
Abstract: AIM The comparative efficacy, safety and tolerability of budesonide-MMX and oral mesalamine in active, mild-to-moderate ulcerative colitis (UC) are unclear. We conducted a network meta-analysis to fill this evidence gap. METHODS We searched PubMed, Scopus,… read more here.
Keywords: mesalamine; budesonide mmx; mesalamine day; active mild ... See more keywords
Mesalamine induced hepatotoxicity. Is mesalamine safe?
Sign Up to like & getrecommendations! Published in 2024 at "Revista espanola de enfermedades digestivas"
DOI: 10.17235/reed.2024.10131/2023
Abstract: Dear Editor: Mesalamine is a medication used widely in the treatment of patients with inflammatory bowel disease. Although mesalamine is considered safe, hepatotoxicity has been reported with an incidence of 0-4%. We present the clinical… read more here.
Keywords: mesalamine; hepatotoxicity mesalamine; mesalamine induced; mesalamine safe ... See more keywords
Mebendazole as an Adjunct Therapy with Mesalamine to Increase Efficacy and Maintenance Therapy for Ulcerative Colitis Patients: A Pilot Study.
Sign Up to like & getrecommendations! Published in 2025 at "Current pharmaceutical design"
DOI: 10.2174/0113816128372513250616182826
Abstract: BACKGROUND Ulcerative colitis (UC) is an inflammatory disorder of the large intestine characterized by inflammation in the mucosal tissue of the colon and rectal area. In the present pilot study, we assessed the efficacy of… read more here.
Keywords: mesalamine; therapy; pilot; efficacy ... See more keywords
Determination of Mesalamine in Bulk and Suppository Dosage Forms through the Development and Validation of Stability- indicating RPHPLC Method
Sign Up to like & getrecommendations! Published in 2024 at "Current Pharmaceutical Analysis"
DOI: 10.2174/0115734129308140240715052552
Abstract: In the current study, a simple and cost-effective stability-indicating RP-HPLC method was developed and validated to estimate the mesalamine from both bulk and pharmaceutical dosage forms. An isocratic HPLC method using a reverse phase HiQSilC18… read more here.
Keywords: mesalamine; method; degradation; dosage forms ... See more keywords
Solvent-free Hot Melt Extrusion Technique in Improving Mesalamine Release for Better Management of Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Pharmaceutical Education and Research"
DOI: 10.5530/ijper.53.4s.150
Abstract: Background: Poor oral bioavailability of mesalamine (Mes) is due to extensive metabolism in the intestinal epithelial cells in addition to the liver. Purpose: Improved mesalamine release by Hot-Melt Extrusion (HME) technique could be utilized for… read more here.
Keywords: mesalamine; melt extrusion; hot melt; mesalamine release ... See more keywords