Solvent-free Hot Melt Extrusion Technique in Improving Mesalamine Release for Better Management of Inflammatory Bowel Disease
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DOI: 10.5530/ijper.53.4s.150
Abstract: Background: Poor oral bioavailability of mesalamine (Mes) is due to extensive metabolism in the intestinal epithelial cells in addition to the liver. Purpose: Improved mesalamine release by Hot-Melt Extrusion (HME) technique could be utilized for… read more here.
Keywords: mesalamine; melt extrusion; hot melt; mesalamine release ... See more keywords