AGO1 regulates pericentromeric regions in mouse embryonic stem cells
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DOI: 10.1101/2021.07.26.453733
Abstract: Depletion of AGO1 in mESCs leads to a redistribution of H3K9me3 and HP1α away from pericentromeric regions and is accompanied by an up-regulation of major satellites transcripts. Argonaute proteins (AGOs), which play an essential role… read more here.
Keywords: ago1; embryonic stem; mescs; mouse embryonic ... See more keywords
EGFR deficiency leads to impaired self-renewal and pluripotency of mouse embryonic stem cells
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DOI: 10.7717/peerj.6314
Abstract: Background Self-renewal and pluripotency are considered as unwavering features of embryonic stem cells (ESCs). How ESCs regulate the self-renewal and differentiation is a central question in development and regenerative medicine research. Epidermal growth factor receptor… read more here.
Keywords: egfr inhibition; renewal pluripotency; pluripotency; self renewal ... See more keywords