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   Articles with "mesenchymal chondrosarcoma" as a keyword



Mesenchymal chondrosarcoma of the head and neck with HEY1::NCOA2 fusion: A clinicopathologic and molecular study of 13 cases with emphasis on diagnostic pitfalls

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recommendations! Published in 2022 at "Genes"

DOI: 10.1002/gcc.23075

Abstract: Mesenchymal chondrosarcoma (MCS) is a rare translocation‐associated sarcoma, driven by a canonical HEY1::NCOA2 fusion. The tumors typically have a biphasic phenotype of primitive small blue round cells intermixed with hyaline cartilage. The head and neck… read more here.

Keywords: head neck; mesenchymal chondrosarcoma; ncoa2 fusion; chondrosarcoma head ... See more keywords

Renal Extra Skeletal Mesenchymal Chondrosarcoma: A Case Report

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recommendations! Published in 2017 at "Urology Case Reports"

DOI: 10.1016/j.eucr.2016.12.013

Abstract: Primary mesenchymal chondrosarcoma of the Kidney is an extremely rare entity and very few cases have been reported in literature. We report a 22-year-old male with a right renal mass; after radical nephrectomy, pathologic examination… read more here.

Keywords: chondrosarcoma; skeletal mesenchymal; extra skeletal; report ... See more keywords

Minute mesenchymal chondrosarcoma within osteochondroma: an unexpected diagnosis confirmed by HEY1-NCOA2 fusion.

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recommendations! Published in 2018 at "Human pathology"

DOI: 10.1016/j.humpath.2018.03.014

Abstract: Mesenchymal chondrosarcoma is rare and can be challenging to diagnose. Herein, we report a minute mesenchymal chondrosarcoma within an osteochondroma. A 12-year-old girl presented with an asymptomatic exophytic lesion of the rib. The tumor was… read more here.

Keywords: chondrosarcoma; within osteochondroma; chondrosarcoma within; mesenchymal chondrosarcoma ... See more keywords

Primary spinal intradural extramedullary mesenchymal chondrosarcoma: a case report.

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recommendations! Published in 2020 at "World neurosurgery"

DOI: 10.1016/j.wneu.2020.10.007

Abstract: BACKGROUND Among chondrosarcomas arising from bones and soft tissues, mesenchymal chondrosarcoma (MCS), especially primary spinal intradural extramedullary MCS, is extremely rare, and only 18 cases have been reported to date. We report an adult case… read more here.

Keywords: primary spinal; mcs; intradural extramedullary; case ... See more keywords

Bilateral renal metastases from extraskeletal mesenchymal chondrosarcoma of thigh

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recommendations! Published in 2022 at "BMJ Case Reports"

DOI: 10.1136/bcr-2021-246375

Abstract: Mesenchymal chondrosarcoma (MC) is a rare cartilaginous tumour that occurs in the extraskeletal locations in about one-third of cases. It is aggressive in behaviour and may involve the lower extremities, central nervous system or spine.… read more here.

Keywords: extraskeletal mesenchymal; metastases extraskeletal; mesenchymal chondrosarcoma; bilateral renal ... See more keywords
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NKX3.1 immunohistochemistry and methylome profiling in mesenchymal chondrosarcoma: additional diagnostic value for a well-defined disease?

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recommendations! Published in 2023 at "Pathology"

DOI: 10.1158/1538-7445.am2023-6218

Abstract: Mesenchymal chondrosarcoma (MCS) is a rare and highly aggressive tumour of soft tissue and bone that is defined by an underlying and highly specific fusion transcript involving HEY1 and NCOA2. Histologically, the tumours show a… read more here.

Keywords: component; mesenchymal chondrosarcoma; diagnostic value; round cell ... See more keywords
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Mesenchymal chondrosarcoma: An Australian multi-centre cohort study.

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recommendations! Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.15_suppl.e23509

Abstract: e23509Background: Mesenchymal chondrosarcoma (MCS) is a rare sarcoma that has a more aggressive course than conventional chondrosarcoma. Treatment is often multimodal with combinations of surgery, ... read more here.

Keywords: chondrosarcoma; centre cohort; multi centre; chondrosarcoma australian ... See more keywords

Case report: A mesenchymal chondrosarcoma with alternative HEY1::NCOA2 fusions in the sella turcica

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recommendations! Published in 2024 at "Pathology and Oncology Research"

DOI: 10.3389/pore.2024.1611730

Abstract: Introduction Mesenchymal chondrosarcoma (MCS) is a rare subtype of chondrosarcoma that occurs at widespread anatomical locations, such as bone, soft tissue, and intracranial sites. The central nervous system (CNS) is one of the most common… read more here.

Keywords: hey1 ncoa2; hey1; alternative hey1; report ... See more keywords

Chemotherapy Strategies and Their Efficacy for Mesenchymal Chondrosarcoma

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recommendations! Published in 2025 at "Current Oncology"

DOI: 10.3390/curroncol32110615

Abstract: Simple Summary Mesenchymal chondrosarcoma (MCS) is characterised by small round cell biology with frequent HEY1-NCOA2 fusion, early haematogenous spread, and greater sensitivity to systemic chemotherapy (CHT) than other chondrosarcoma subtypes. CHT is used in both… read more here.

Keywords: mesenchymal chondrosarcoma; chemotherapy strategies; strategies efficacy; chondrosarcoma ... See more keywords

Extraskeletal Mesenchymal Chondrosarcoma of Central Nervous System – A Rare but Aggressive Tumor: Analysis of Five Cases

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recommendations! Published in 2022 at "Neurology India"

DOI: 10.4103/0028-3886.338726

Abstract: Background: Extraskeletal mesenchymal chondrosarcoma (MCS) of the central nervous system (CNS) is extremely rare. Herein, we present the clinicopathological features of five CNS extraskeletal MCS. Material and Methods: Over the past 10 years, five cases… read more here.

Keywords: extraskeletal mesenchymal; mesenchymal chondrosarcoma; central nervous; five cases ... See more keywords

Extraskeletal mesenchymal chondrosarcoma at unusual location involving spleen and kidney with review of literature

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recommendations! Published in 2017 at "Indian Journal of Pathology and Microbiology"

DOI: 10.4103/ijpm.ijpm_16_16

Abstract: Mesenchymal chondrosarcoma (MC) is a rare malignant neoplasm bearing characteristic dimorphic pattern histologically. We describe two rare cases of primary MC involving two different visceral organs (1) a 24-year-old man with solid renal mass and,… read more here.

Keywords: chondrosarcoma; location involving; chondrosarcoma unusual; unusual location ... See more keywords