Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04179-8
Abstract: Gastric cancer is a heterogeneous cancer, making treatment responses difficult to predict. Here we show that we identify two distinct molecular subtypes, mesenchymal phenotype (MP) and epithelial phenotype (EP), by analyzing genomic and proteomic data.… read more here.
Keywords: subtype associated; mesenchymal phenotype; gastric cancer; subtype tumors ... See more keywords
NRF2-dependent Epigenetic Regulation can Promote the Hybrid Epithelial/Mesenchymal Phenotype
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DOI: 10.3389/fcell.2021.828250
Abstract: The epithelial-mesenchymal transition (EMT) is a cellular process critical for wound healing, cancer metastasis and embryonic development. Recent efforts have identified the role of hybrid epithelial/mesenchymal states, having both epithelial and mesehncymal traits, in enabling… read more here.
Keywords: epigenetic regulation; hybrid epithelial; mesenchymal phenotype; epithelial mesenchymal ... See more keywords
Dental pulp stem cells retain mesenchymal phenotype despite differentiation toward retinal neuronal fate in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.821361
Abstract: Dental pulp stem cells (DPSCs) are an easily accessible, heterogenous source of mesenchymal stem cells (MSCs) that are derived from the neural crest. Evidence suggests that they have neurotrophic qualities in their undifferentiated state and… read more here.
Keywords: dental pulp; phenotype despite; mesenchymal phenotype; pulp stem ... See more keywords