RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance
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DOI: 10.1016/j.ccell.2019.05.015
Abstract: Summary RAC1 P29 is the third most commonly mutated codon in human cutaneous melanoma, after BRAF V600 and NRAS Q61. Here, we study the role of RAC1P29S in melanoma development and reveal that RAC1P29S activates… read more here.
Keywords: melanoma; mesenchymal phenotypic; rac1p29s; resistance ... See more keywords