Proteomic analysis of the IPF mesenchymal progenitor cell nuclear proteome identifies abnormalities in key nodal proteins that underlie their fibrogenic phenotype
Sign Up to like & getrecommendations! Published in 2022 at "Proteomics"
DOI: 10.1002/pmic.202200018
Abstract: IPF is a progressive fibrotic lung disease whose pathogenesis remains incompletely understood. We have previously discovered pathologic mesenchymal progenitor cells (MPCs) in the lungs of IPF patients. IPF MPCs display a distinct transcriptome and create… read more here.
Keywords: ipf; phenotype; progenitor; mesenchymal progenitor ... See more keywords
Shotgun proteomic analysis of the secretome of bovine endometrial mesenchymal progenitor/stem cells challenged or not with bacterial lipopolysaccharide.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2017.03.007
Abstract: The use of the conditioned medium (CM) for diseases treatment is based on its enrichment with biomolecules with therapeutic properties and themselves have a beneficial effect. Secretome of bovine endometrial mesenchymal progenitor/stem cells (eMSCs) using… read more here.
Keywords: progenitor stem; bovine; endometrial mesenchymal; mesenchymal progenitor ... See more keywords
Production of Mesenchymal Progenitor Cell-Derived Extracellular Vesicles in Suspension Bioreactors for Use in Articular Cartilage Repair
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szab008
Abstract: Abstract Mesenchymal progenitor cells (MPCs) have shown promise initiating articular cartilage repair, with benefits largely attributed to the trophic factors they secrete. These factors can be found in the conditioned medium (CM) collected from cell… read more here.
Keywords: extracellular vesicles; cartilage; mesenchymal progenitor; cartilage repair ... See more keywords
Ptip is essential for tooth development via regulating Wnt pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Oral diseases"
DOI: 10.1111/odi.14509
Abstract: OBJECTIVE Epigenetic regulation plays important role in stem cell maintenance. Ptip was identified as epigenetic regulator, but the role in dental progenitor cells remains unclear. SUBJECTS AND METHODS Dental mesenchymal progenitor cells were targeted by… read more here.
Keywords: progenitor; sp7 icre; mesenchymal progenitor; lower incisors ... See more keywords
Mouse Mesenchymal Progenitor Cells Expressing Adipogenic and Osteogenic Transcription Factors Suppress the Macrophage Inflammatory Response
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells International"
DOI: 10.1155/2017/5846257
Abstract: Mesenchymal progenitor cell characteristics that can identify progenitor populations with specific functions in immunity are actively being investigated. Progenitors from bone marrow and adipose tissue regulate the macrophage (MΦ) inflammatory response by promoting the switch… read more here.
Keywords: transcription factors; response; mesenchymal progenitor; inflammatory ... See more keywords
Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Investigation"
DOI: 10.1172/jci88629
Abstract: Pulmonary vascular disease is characterized by remodeling and loss of microvessels and is typically attributed to pathological responses in vascular endothelium or abnormal smooth muscle cell phenotypes. We have challenged this understanding by defining an… read more here.
Keywords: adult; lineage; mesenchymal progenitor; mpcs ... See more keywords
Human Embryonic-Derived Mesenchymal Progenitor Cells (hES-MP Cells) are Fully Supported in Culture with Human Platelet Lysates
Sign Up to like & getrecommendations! Published in 2020 at "Bioengineering"
DOI: 10.3390/bioengineering7030075
Abstract: Human embryonic stem cell-derived mesenchymal progenitor (hES-MP) cells are mesenchymal-like cells, derived from human embryonic stem cells without the aid of feeder cells. They have been suggested as a potential alternative to mesenchymal stromal cells… read more here.
Keywords: medicine; derived mesenchymal; mesenchymal progenitor; hes cells ... See more keywords
Microbial Sterility Testing for Mesenchymal Progenitor Cells Derived from Human Osteoarthritis and Rheumatoid Arthritis Cartilage.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical laboratory"
DOI: 10.7754/clin.lab.2022.211043
Abstract: BACKGROUND The goal is to evaluate the microbial sterility of mesenchymal progenitor cells (MPCs)-derived from osteoarthritis (OA) and rheumatoid arthritis (RA) articular cartilages. METHODS Contaminants, including bacteria and fungi in MPC cultures were initially evaluated… read more here.
Keywords: osteoarthritis rheumatoid; rheumatoid arthritis; mesenchymal progenitor; sterility ... See more keywords