Mesenchymal stroma: Role in osteosarcoma progression.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.07.024
Abstract: The initiation and progression of malignant tumors are supported by their microenvironment: cancer cells per se cannot explain growth and formation of the primary or metastasis, and a combination of proliferating tumor cells, cancer stem… read more here.
Keywords: progression; role; cancer; osteosarcoma progression ... See more keywords
Reversible switching of leukemic cells to a drug-resistant, stem-like subset via IL-4 mediated cross-talk with mesenchymal stroma.
Sign Up to like & getrecommendations! Published in 2021 at "Haematologica"
DOI: 10.3324/haematol.2020.269944
Abstract: Chemoresistance of leukemic cells has largely been attributed to clonal evolution secondary to accumulating mutations. Here, we show that a subset of leukemic blasts in contact with the mesenchymal stroma undergo cellular conversion into a… read more here.
Keywords: cross talk; leukemic cells; mesenchymal stroma;