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   Articles with "mesenchymal transformation" as a keyword



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Rebooting the collagen gel: Artificial hydrogels for the study of epithelial mesenchymal transformation

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recommendations! Published in 2018 at "Developmental Dynamics"

DOI: 10.1002/dvdy.24560

Abstract: The collagen gel has been used to study epithelial–mesenchymal transformation (EMT) for over 30 years. With advances in the field of materials sciences, new options are available to design optically clear, three‐dimensional nature‐inspired matrix mimetics… read more here.

Keywords: collagen; collagen gel; study epithelial; mesenchymal transformation ... See more keywords
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A Multiscale In Silico Model of Endothelial to Mesenchymal Transformation in a Tumor Microenvironment.

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recommendations! Published in 2019 at "Journal of theoretical biology"

DOI: 10.1016/j.jtbi.2019.08.012

Abstract: Endothelial to mesenchymal transformation (EndMT) is a process in which endothelial cells gain a mesenchymal-like phenotype in response to mechanobiological signals that results in the remodeling or repair of underlying tissue. While initially associated with… read more here.

Keywords: endothelial mesenchymal; mesenchymal transformation; model; tumor microenvironment ... See more keywords
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Epithelial–mesenchymal transformation and apoptosis in rat urethra development

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recommendations! Published in 2017 at "Pediatric Research"

DOI: 10.1038/pr.2017.185

Abstract: BackgroundTo examine the mechanism of urethral seam formation during embryonal development of rat urethra.MethodsTime-mated Sprague–Dawley rats were killed and the genital tubercles of male pups harvested on embryonic day (ED) 15, 16, 18, and 19.… read more here.

Keywords: development; urethral seam; epithelial mesenchymal; mesenchymal transformation ... See more keywords
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TMIC-58. THE CELLULAR AND MOLECULAR BASIS FOR MESENCHYMAL TRANSFORMATION IN GLIOMAS

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recommendations! Published in 2019 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noz175.1092

Abstract: Mesenchymal gliomas are the most aggressive tumors that carry the worst prognosis. The origins of mesenchymal cells within brain tumors, remains poorly understood. They could originate either from invading mesenchymal cells, from perivascular smooth muscle… read more here.

Keywords: gliomas; mesenchymal transformation; transformation; progression ... See more keywords
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Abstract 5103: Notch is a master regulator of mesenchymal transformation and therapeutic resistance in glioma

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recommendations! Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-5103

Abstract: Introduction: Gliomas are highly infiltrative tumors rendering complete resection impossible. As such, prognosis remains dismal. Recent studies have identified both proneural and mesenchymal cell populations. Crucially, recurring gliomas bear a mesenchymal phenotype. Understanding mechanisms driving… read more here.

Keywords: glioma; mesenchymal transformation; notch; transformation ... See more keywords