Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple-negative breast cancer.
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DOI: 10.1172/jci.insight.94296
Abstract: The complex signaling networks of the tumor microenvironment that facilitate tumor growth and progression toward metastatic disease are becoming a focus of potential therapeutic options. The chemokine IL-8 is overexpressed in multiple cancer types, including… read more here.
Keywords: breast cancer; cancer; claudin low; mesenchymalization ... See more keywords