A Role of Caveolae in Trabecular Meshwork Mechanosensing and Contractile Tone
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DOI: 10.3389/fcell.2022.855097
Abstract: Polymorphisms in the CAV1/2 gene loci impart increased risk for primary open-angle glaucoma (POAG). CAV1 encodes caveolin-1 (Cav1), which is required for biosynthesis of plasma membrane invaginations called caveolae. Cav1 knockout mice exhibit elevated intraocular… read more here.
Keywords: contractile tone; cav1; trabecular meshwork; caveolae ... See more keywords