Stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25180
Abstract: To evaluate the outcomes 1 year and longer following stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy in a large series of patients treated over a 5‐year period since introduction of this novel technique. read more here.
Keywords: lobe epilepsy; mesial temporal; amygdalohippocampotomy mesial; temporal lobe ... See more keywords
Rare Genetic Variation and Outcome of Surgery for Mesial Temporal Lobe Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26581
Abstract: Genetic factors have long been debated as a cause of failure of surgery for mesial temporal lobe epilepsy (MTLE). We investigated whether rare genetic variation influences seizure outcomes of MTLE surgery. read more here.
Keywords: surgery; lobe epilepsy; rare genetic; temporal lobe ... See more keywords
Network of ictal head version in mesial temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1820
Abstract: Ictal head version is a common clinical manifestation of mesial temporal lobe epilepsy (MTLE). Nevertheless, the location of the symptomatogenic zone and the network involved in head version remains unclear. We attempt to explain these… read more here.
Keywords: head; mesial temporal; head version; temporal lobe ... See more keywords
Frequency‐specific network changes in mesial temporal lobe epilepsy: Analysis of chronic and transient dysfunctions in the temporo‐amygdala‐orbitofrontal network using magnetoencephalography
Sign Up to like & getrecommendations! Published in 2025 at "Epilepsia Open"
DOI: 10.1002/epi4.70018
Abstract: Mesial temporal lobe epilepsy (MTLE) is associated with disruptions in the temporo‐amygdala‐orbitofrontal (TAO) network, a key component of the limbic system. We aimed to investigate TAO network alterations in patients with MTLE using magnetoencephalography (MEG),… read more here.
Keywords: lobe epilepsy; temporal lobe; temporo amygdala; network ... See more keywords
Graph theoretical analysis of evoked potentials shows network influence of epileptogenic mesial temporal region
Sign Up to like & getrecommendations! Published in 2021 at "Human Brain Mapping"
DOI: 10.1002/hbm.25418
Abstract: It is now widely accepted that seizures arise from the coordinated activity of epileptic networks, and as a result, traditional methods of analyzing seizures have been augmented by techniques like single‐pulse electrical stimulation (SPES) that… read more here.
Keywords: mesial temporal; network; effective connectivity; epileptogenic mtr ... See more keywords
Compartment-specific small non-coding RNA changes and nucleolar defects in human mesial temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2024 at "Acta Neuropathologica"
DOI: 10.1007/s00401-024-02817-8
Abstract: Mesial temporal lobe epilepsy (mTLE) is a debilitating disease characterized by recurrent seizures originating from temporal lobe structures such as the hippocampus. The pathogenic mechanisms underlying mTLE are incompletely understood but include changes in the… read more here.
Keywords: non coding; lobe epilepsy; temporal lobe; lobe ... See more keywords
The Study of Genetic Susceptibility and Mitochondrial Dysfunction in Mesial Temporal Lobe Epilepsy
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01993-4
Abstract: The aim of this study is to investigate the mitochondrial dysfunction and pathogenic role of the mitochondrial genome in the progression of mesial temporal lobe epilepsy (MTLE) in vivo and in vitro. Mitochondrial DNA (mtDNA)… read more here.
Keywords: temporal lobe; lobe epilepsy; mesial temporal; mitochondrial dysfunction ... See more keywords
Volumetric Changes in Hippocampal Subregions and Memory Performance in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-017-0186-2
Abstract: In the present study we explored the different patterns of volumetric atrophy in hippocampal subregions of patients with left and right mesial temporal lobe epilepsy with hippocampal sclerosis (TLE-HS). Meanwhile, the memory impairment patterns in… read more here.
Keywords: lobe epilepsy; mesial temporal; hippocampal subregions; epilepsy hippocampal ... See more keywords
NLRP3 and NLRP1 inflammasomes are up-regulated in patients with mesial temporal lobe epilepsy and may contribute to overexpression of caspase-1 and IL-β in sclerotic hippocampi
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research"
DOI: 10.1016/j.brainres.2020.147230
Abstract: Inflammation plays a role in the pathophysiology of mesial temporal lobe epilepsy (MTLE). Inflammasome pathways, including the NLRP1 and NLRP3-induced ones, promote neuroinflammation and pyroptosis through interleukin (IL)-1β and caspase-1 action. Evaluation of NLRP1 in… read more here.
Keywords: lobe epilepsy; caspase; mesial temporal; hippocampi ... See more keywords
Lateralizing magnetic resonance imaging findings in mesial temporal sclerosis and correlation with seizure and neurocognitive outcome after temporal lobectomy
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2021.106562
Abstract: BACKGROUND Mesial temporal sclerosis (MTS) is the most common cause of temporal lobe epilepsy (TLE). While MTS is associated with a high cure rate after temporal lobectomy (TL), postoperative neurocognitive deficits are common, and a… read more here.
Keywords: mesial temporal; temporal sclerosis; magnetic resonance; temporal lobectomy ... See more keywords
Modulation of NMDA receptor by miR-219 in the amygdala and hippocampus of patients with mesial temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.02.024
Abstract: Mesial temporal lobe epilepsy with hippocampal sclerosis is the most frequent form of focal epilepsy in adults, and it is often refractory to drug treatment. Regardless of the efforts on developing new antiepileptic drugs for… read more here.
Keywords: epilepsy; lobe epilepsy; mesial temporal; amygdala hippocampus ... See more keywords