Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase activity.
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DOI: 10.1016/j.cbi.2018.10.023
Abstract: Nafamostat mesilate is a serine protease inhibitor and used for the treatment of pancreatitis and cancers. The fat mass and obesity-associated protein (FTO) was identified to be a demethylase and played an important role in… read more here.
Keywords: protein; nafamostat mesilate; fat mass; mass obesity ... See more keywords