Mutations in LRP5 and BMP4 are associated with mesiodens, tooth agenesis, root malformation, and oral exostoses
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DOI: 10.1111/cge.14183
Abstract: WNT/β‐catenin and BMP signaling pathways play important roles in the process of tooth development. Dysregulation of WNT/β‐catenin and BMP signaling is implicated in a number of human malformations, including dental anomalies. Whole exome and Sanger… read more here.
Keywords: oral exostoses; agenesis; dental anomalies; mutations lrp5 ... See more keywords