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Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szac080
Abstract: Abstract Chronic kidney disease of unknown cause (CKDu), also known as Mesoamerican nephropathy, typically presents as an ischemic nephropathy with chronic tubulointerstitial fibrosis in normotensive patients, rapidly progressing to kidney failure. In this first-in-human, open-label,…
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Keywords:
disease unknown;
kidney;
chronic kidney;
mesoamerican nephropathy ... See more keywords
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Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0240988
Abstract: Background Although there are several hypothesized etiologies of Mesoamerican Nephropathy (MeN), evidence has not yet pointed to the underlying cause. Exposure to various trace elements can cause the clinical features observed in MeN. Methods and…
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Keywords:
mesoamerican nephropathy;
control analysis;
evidence;
case control ... See more keywords
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Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13030325
Abstract: Mesoamerican nephropathy (MeN) is a form of chronic kidney disease found predominantly in young men in Mesoamerica. Strenuous agricultural labor is a consistent risk factor for MeN, but the pathophysiologic mechanism leading to disease is…
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Keywords:
mesoamerican nephropathy;
risk;
energy metabolism;
metabolic features ... See more keywords